新疆维吾尔族老年男性代谢综合征人群与骨密度的相关性研究

发布时间：2019-06-15 09:26

【摘要】：目的探讨新疆维吾尔族老年男性代谢综合征(metabolic syndrome,MS)与骨密度(bone mineral density,BMD)的相关性。方法采用双能X线吸收测定法检测366例[分为MS组(236例)和非MS组(130例)]新疆维吾尔族老年男性的骨密度,通过全自动生化分析仪检测空腹血糖(fasting blood glucose,FBG)、总胆固醇(total cholesterol,TC)、甘油三酯(triglyceride,TG)、高密度脂蛋白胆固醇(high density lipoprotein cholesterol,HDL-C)、低密度脂蛋白胆固醇(low density lipoprotein cholesterol,LDL-C)、血钙(Ca)、25羟维生素D[25(OH)D]、血清总睾酮(T)、血红蛋白(Hb),测量血压[血管收缩压(systolic blood pressure,SBP)和血管舒张压(diastolic blood pressure,DBP)],测量身高、体重,计算体质量指数(body mass index,BMI)。结果新疆维吾尔族老年男性MS患者骨质疏松检出率高于非MS组,MS组与非MS组间年龄、BMI、FBG、HDL-C、SBP、DBP组间差异有统计学意义(P0.05)。无论是否为MS患者,骨质疏松患者Hb、TC、HDL-C均低于非骨质疏松患者(P0.05)。MS组中骨质疏松患者BMI低于非骨质疏松患者,非MS组中非骨质疏松患者25(OH)D高于骨质疏松患者(P0.05)。骨密度与HDL-C的水平呈负相关(标化B=-0.538,P=0.003),与BMI呈正相关(标化B=0.054,P=0.002),与Hb呈正相关(标化B=0.022,P=0.000)。结论新疆维吾尔族老年男性代谢综合征患者发生骨质疏松的风险取决于各影响因素间的平衡。
[Abstract]:Objective to investigate the relationship between metabolic syndrome (metabolic syndrome,MS) and bone mineral density (bone mineral density,BMD) in elderly men of Uygur nationality in Xinjiang. Methods Bone mineral density (bone mineral density), fasting blood glucose (fasting blood glucose,FBG), total cholesterol (total cholesterol,TC), glycerol (triglyceride,TG), high density lipoprotein cholesterol (high density lipoprotein cholesterol,HDL-C) and low density lipoprotein cholesterol (low density lipoprotein cholesterol,) were measured by dual energy X-ray absorptiometry in 366 elderly men [divided into MS group (n = 236) and non-MS group (n = 130)]. Fasting blood glucose (fasting blood glucose,FBG), total cholesterol (triglyceride,TG), high density lipoprotein cholesterol (high density lipoprotein cholesterol,HDL-C) and low density lipoprotein cholesterol (LDL) were measured by automatic biochemical analyzer. LDL-C), serum calcium (Ca), 25 hydroxyvitamin D [25 (OH) D], serum total testosterone (T), hemoglobin (Hb), measured blood pressure [systolic blood pressure (systolic blood pressure,SBP) and diastolic blood pressure (diastolic blood pressure,DBP)], height, weight and body mass index (body mass index,BMI) were measured. Results the detection rate of osteoporosis in elderly men with MS in Xinjiang Uygur nationality was higher than that in non-MS group. There were significant differences in age and BMI,FBG,HDL-C,SBP,DBP between MS group and non-MS group (P 0.05). Whether it was MS or not, the Hb,TC,HDL-C of osteoporotic patients was lower than that of non-osteoporotic patients (P 0.05). The BMI of osteoporotic patients in). MS group was lower than that of non-osteoporotic patients, and the 25 (OH) D of non-osteoporotic patients in non-MS group was higher than that of osteoporotic patients (P 0.05). Bone mineral density was negatively correlated with the level of HDL-C (standardized B 鈮，

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