2型糖尿病患者认知功能改变及其危险因素

发布时间：2019-07-09 20:31

【摘要】：目的了解2型糖尿病(T2DM)患者认知功能损害的情况及其危险因素。方法应用简易智能精神状态量表(MMSE)评估年龄、性别、文化程度和居住地相匹配的250例T2DM患者和250例对照者的认知功能,并将糖尿病组按年龄、病程、血糖控制水平、并发症与认知功能障碍进行单因素分析。结果糖尿病组MMSE总分,尤其是记忆、注意与计算力、语言能力、视空间、时间和地点定向得分显著低于对照组(P0.05,P0.01)。糖尿病组认知功能障碍与年龄、病程、血糖控制水平、合并高血压、高血脂、冠心病等因素均有统计学意义(P0.05;P0.01)。未发现糖尿病治疗方法与认知功能有明显的关系。结论认知功能减退与T2DM有关。严格控制血糖、血压,调整血脂等手段是改善认知功能的重要措施。
[Abstract]:Objective to investigate the cognitive impairment and its risk factors in patients with type 2 diabetes mellitus (T2DM). Methods the cognitive function of 250 T2DM patients and 250 controls matched with age, sex, educational level and place of residence were evaluated by simple Mental State scale (MMSE). Univariate analysis was made on the cognitive function of diabetic group according to age, course of disease, blood glucose control level, complications and cognitive impairment. Results the total score of MMSE, especially memory, attention and calculation, language ability, visual space, time and place orientation, in diabetic group were significantly lower than those in control group (P0.05, P0.01). In diabetic group, cognitive impairment and age, course of disease, blood glucose control level, hypertension, hyperlipidemia, coronary heart disease and other factors were statistically significant (P0.05 鈮，

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