消风散加减方联合NB-UVB治疗玫瑰糠疹风热证的临床疗效观察

发布时间：2017-12-27 21:03

本文关键词：消风散加减方联合NB-UVB治疗玫瑰糠疹风热证的临床疗效观察　出处：《南京中医药大学》2016年硕士论文　论文类型：学位论文

【摘要】：目的：观察消风散加减方联合窄谱中波紫外线(NB-UVB)治疗玫瑰糠疹风热证型的临床疗效及安全性。方法：将2015年4月至12月于江苏省中医院皮肤科就诊的40例玫瑰糠疹风热证型患者随机分成两组,治疗组及对照组各20例。治疗组予口服消风散加减方,对照组予口服花藤子颗粒,两组均接受窄谱中波紫外线照射治疗及外用黄芩油膏。疗程两周,每周复诊一次。使用PRSS评分法评估患者症状及体征,并记录患者有无不良反应发生,一个疗程结束电话随访至患者皮疹消退。结果：两组治疗均有效果,治疗1周后和2周后比较,治疗组PRSS积分均低于对照组,疗效指数均高于对照组,差异比较具有显著性(P0.05)。一个疗程后治疗组总有效率达95%,对照组总有效率为65%(P0.05)。治疗前后,治疗组对于红斑、浸润、鳞屑和瘙痒的疗效上均优于对照组(P0.05),在皮疹数量改善上无明显差异(P0.05)。治疗组皮疹消退时间21.45±3.93天,对照组26.90±6.39天,差异比较具有统计学意义(P0.05)。在治疗期及随访期间,两组均未出现明显不良反应,发生率为0。结论：消风散加减方联合NB-UVB治疗玫瑰糠疹风热证型安全有效,无明显不良发应发生。与花藤子颗粒组对比,疗效更优。
[Abstract]:Objective: To observe the effect of xiaofengsan decoction combined with narrow-band ultraviolet (NB-UVB) clinical efficacy and safety of the treatment of pityriasis rosea windheat syndrome type. Methods: from April 2015 to December in the Department of Dermatology of Jiangsu Province Traditional Chinese Medicine Hospital for treatment of 40 cases of pityriasis rosea windheat syndrome type were randomly divided into two groups, treatment group and control group of 20 cases. The treatment group was given oral Xiaofeng powder plus or minus side, and the control group was given oral Ka Fujiko granules. The two groups were treated with ultraviolet light ultraviolet radiation therapy and external use Scutellaria ointment. Two weeks of treatment, once a week. The PRSS score was used to assess the symptoms and signs of the patients and to record the patients' adverse reactions. A course of treatment was followed up to the patient's rash. Results: the two groups were effective. After 1 weeks and 2 weeks, the PRSS score in the treatment group was lower than that in the control group, and the curative effect index was higher than that in the control group. The difference was statistically significant (P0.05). After a course of treatment, the total effective rate of the treatment group was 95%, and the total effective rate of the control group was 65% (P0.05). Before and after treatment, the curative effect of the treatment group on erythema, infiltration, scaly and pruritus was better than that of the control group (P0.05), and there was no significant difference in the improvement of the number of rashes (P0.05). The regression time of rash in the treatment group was 21.45 + 3.93 days, and the control group was 26.90 + 6.39 days, the difference was statistically significant (P0.05). During the period of treatment and follow-up, there was no obvious adverse reaction in the two groups, and the incidence was 0. Conclusion: xiaofengsan decoction combined with NB-UVB is effective in the treatment of pityriasis windheat syndrome type rose safety, no obvious adverse reaction occurred. Compared with the Ka Fujiko granule group, the curative effect was better.
【学位授予单位】：南京中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R758.64

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