5-氨基酮戊酸光动力疗法治疗面部扁平疣临床分析

发布时间：2018-01-03 18:05

本文关键词：5-氨基酮戊酸光动力疗法治疗面部扁平疣临床分析　出处：《激光杂志》2015年05期 　论文类型：期刊论文

【摘要】：分析5-氨基酮戊酸光动力疗法(ALA-PDT)治疗面部扁平疣的疗效。将91例患者随机分为治疗组(45例)和对照组(46例),治疗组予ALA-PDT,每10天1次,共4次;对照组采用卡介菌多糖核酸注射液肌注,每次2m L,隔日1次,同时以干扰素凝胶外用于患处,1日4次,共2个月。两组均随访3个月治疗组显效率(93.33%)明显高于对照组(76.09%)(P0.05),而治疗组总有效率(100%)亦高于对照组(89.13%),但无统计学意义(P0.05);治疗结束后3个月随访,治疗组显效率(91.11%)与总有效率(100%)分别明显高于对照组的显效率(69.57%)与总有效率(86.96%)(P0.05)。ALA-PDT是治疗面部扁平疣的一种有效、安全的方法。
[Abstract]:To analyze the efficacy of 5-aminolevulinic acid photodynamic therapy (ALA-PDT) in the treatment of facial verruca plana, 91 patients were randomly divided into treatment group (n = 45) and control group (n = 46). The treatment group was treated with ALA-PDT once every 10 days for 4 times. In the control group, BCG polysaccharide nucleic acid injection was injected intramuscularly, 2 m L every time, once every other day, and at the same time, the interferon gel was used in the affected area 4 times in 1st. The effective rate of the treatment group was significantly higher than that of the control group (P 0.05). The total effective rate in the treatment group was higher than that in the control group (P < 0.01), but there was no significant difference between the treatment group and the control group (P 0.05). The patients were followed up for 3 months after treatment. The effective rate of the treatment group (91.11) and the total effective rate (100) were significantly higher than those of the control group (69.57) and the total effective rate of 86.96% (P0.05). ALA-PDT is an effective treatment for facial verruca plana. A safe way.
【作者单位】：南京医科大学附属无锡二院皮肤科;
【分类号】：R752.5;R454.2
【正文快照】： 扁平疣(plane warts)是临床上较为常见的皮肤病,传统的免疫调节、激光、冷冻等方法均有一定的疗效[1],但存在起效慢、疗效不显著、遗留疤痕、色素沉着等种种局限性,我科在2009年12月至2013年10月采用5-氨基酮戊酸光动力疗法(ALA-PDT)治疗扁平疣患者,取得了较好的疗效,现总结报

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