脉冲染料激光联合咪喹莫特治疗鲜红斑痣的临床研究

发布时间：2018-02-26 01:34

本文关键词： 脉冲染料激光鲜红斑痣咪喹莫特　出处：《实用医学杂志》2014年12期 　论文类型：期刊论文

【摘要】：目的:对脉冲染料激光联合咪喹莫特治疗鲜红斑痣的疗效进行临床分析。方法:15例受试者,每例设计4个区,同一解剖部位的鲜红斑痣上设计3个区:A区为空白对照区;B区为脉冲染料激光联合咪喹莫特治疗区,C区为脉冲染料激光治疗区。对侧正常皮肤为D区。治疗后2个月随访分析其临床疗效。结果:色度值评估中,红型鲜红斑痣9名患者B区和C区的褪色率间存在显著差异,1名患者无效;紫型鲜红斑痣B区和C区的褪色率不存在显著差异,1名患者无效。医生主观评估中,红型鲜红斑痣B区和C区的平均评分分别为(1.9±1.5)分,(1.5±0.8)分;紫型鲜红斑痣B区和C区的平均评分分别为(1.3±0.9)分,C区为(1.3±0.8)分。结论:联合疗法疗效优于单纯的脉冲染料激光治疗,具有与单纯的脉冲染料激光疗法相当的短期安全性,具有较为理想的发展前景。
[Abstract]:Objective: to analyze the efficacy of pulsed dye laser combined with imiquimod in the treatment of nevus Flavus. Three regions were designed on the same anatomical site of nevus chrysalis. The blank control area was area B, the area C was treated by pulsed dye laser combined with imiquimod laser, and the normal skin on the contralateral side was region D. After 2 years of treatment, area C was treated with pulsed dye laser. Results: in the evaluation of chromaticity value, There was a significant difference in fading rate between region B and C in 9 patients with red nevus, but there was no significant difference in fading rate between region B and region C in one patient, but there was no significant difference in fading rate between region B and region C. in the subjective assessment of the doctor, there was no significant difference in the fading rate of one patient. The average scores of red nevus in area B and area C were 1.9 卤1.5 and 1.5 卤0.8, respectively, and those in area B and C of purple nevus were 1.3 卤0.9 and 1.3 卤0.8, respectively. Conclusion: the combined therapy is superior to pulsed dye laser therapy. It has the same short-term safety as pure pulsed dye laser therapy and has an ideal development prospect.
【作者单位】：南方医科大学南方医院整形外科;广州军区广州总医院整形外科;
【基金】：广东省科技计划项目(编号:2010B050700011)
【分类号】：R751.05

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