强脉冲光联合点阵铒激光对痤疮后增生性瘢痕的有效性与安全性分析

发布时间：2018-02-28 04:22

本文关键词： 强脉冲光点阵铒激光痤疮瘢痕　出处：《中国现代医学杂志》2017年25期 　论文类型：期刊论文

【摘要】：目的研究分析强脉冲光联合点阵铒激光对痤疮后增生性瘢痕的有效性与安全性。方法选择上海交通大学附属医学院苏州九龙医院2013年8月-2016年7月收治的135例痤疮后增生性瘢痕患者。采用随机数字表法将其分为强脉冲组、点阵组、联合治疗组,每组45例,比较治疗前和2次治疗后的疗效、温哥华瘢痕评价量表(VSS)评分以及不良反应情况和误工期。结果 3组治疗有效率比较,差异无统计学意义(P0.05),但治疗后3组患者色泽、血管分布、厚度、柔软度和VSS评分比较,差异有统计学意义(P0.05),并均有下降趋势。联合治疗组2次治疗后色泽、血管分布、厚度、柔软度和VSS评分与强脉冲组和点阵饵激光组比较,差异有统计学意义(P0.05),联合治疗组各项指标低于其他两组。治疗后3组患者的生活质量评分比较,差异有统计学意义(P0.05)。治疗后联合治疗组的自我感知、情感功能、痤疮症状、社会功能等生活质量评分与同时期的强脉冲组和点阵铒激光组比较,差异有统计学意义(P0.05),联合治疗组各指标均高于其他两组。联合治疗组的误工期与强脉冲组和点阵铒激光组比较,差异有统计学意义(P0.05),联合治疗组均低于其余两组,但3组不良反应发生率差异无统计学意义(P0.05)。结论强脉冲光联合点阵铒激光治疗痤疮瘢痕具有非常好的疗效,治疗副作用较少,安全性高,同时能够降低误工期,具有广阔的临床应用前景。
[Abstract]:Objective to study the efficacy and safety of intense pulse light combined with lattice erbium laser in the treatment of hypertrophic scar after acne. Methods 135 cases of acnes were selected from August 2013 to July 2016 in Suzhou Jiulong Hospital affiliated to Shanghai Jiaotong University. Patients with hypertrophic scar after ulceration were divided into two groups by random digital table. Results 45 cases in each group were compared before and after treatment, VSSs, VSSs, adverse reactions and delayed working period. Results the effective rate of treatment in the three groups was higher than that in the control group. There was no significant difference in color, blood vessel distribution, thickness, softness and VSS score. The softness and VSS score were significantly different from those in the strong pulse group and the dot array laser group, and the indexes in the combined treatment group were lower than those in the other two groups. After treatment, the scores of self-perception, emotional function, acne symptom, social function and other QOL scores in the combined treatment group were compared with those in the same period strong pulse group and lattice erbium laser group. The difference was statistically significant (P 0.05), and the indexes of the combined treatment group were higher than those of the other two groups. The delayed working period of the combined treatment group was significantly higher than that of the strong pulse group and the lattice erbium laser group, and the combined treatment group was lower than the other two groups. However, there was no significant difference in the incidence of adverse reactions among the three groups (P 0.05). Conclusion the treatment of acne scar with strong pulse light combined with lattice erbium laser has a very good effect, less side effects, higher safety, and can reduce the delayed working period. It has a broad prospect of clinical application.
【作者单位】：上海交通大学附属医学院苏州九龙医院;
【分类号】：R758.733

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