Mohs显微描记手术治疗头面部皮肤恶性肿瘤

发布时间：2018-03-07 22:31

  本文选题：Mohs手术　切入点：皮肤恶性肿瘤　出处：《中国现代医学杂志》2017年18期 　论文类型：期刊论文

【摘要】：目的探讨Mohs显微描记手术治疗头面部基底细胞癌、鳞状细胞癌及鲍温病等皮肤恶性肿瘤的疗效和预后,分析头面部皮肤恶性肿瘤的临床特点。方法该院收治的未见转移的面部皮肤恶性肿瘤患者411例,分为Mohs手术组256例,传统术中冷冻手术组130例,经验切除组25例,并对切取肿瘤创面采用邻近皮瓣、肌皮瓣及游离皮片或直接缝合方式修复。随访3~5年。结果 Mohs手术组248例手术切口Ⅰ期愈合,皮瓣或皮片全部成活,8例Ⅱ期愈合,2例复发(0.8%)。传统术中冷冻手术组125例手术切口Ⅰ期愈合,5例Ⅱ期愈合,7例复发(5.4%)。经验切除组25例均Ⅰ期愈合,4例复发(16%)。各组术后病理复检发现,肿瘤残余和临床复发率差异有统计学意义(P0.01)。结论 Mohs手术可以在完整切除肿瘤的同时尽可能保留正常组织减少外观影响,是目前治疗头面部皮肤恶性肿瘤的首选方案。
[Abstract]:Objective to evaluate the efficacy and prognosis of Mohs micrography in the treatment of skin malignant tumors such as basal cell carcinoma, squamous cell carcinoma and Bowen's disease. Methods the clinical features of malignant tumors of head and face were analyzed. Methods 411 cases of facial malignant tumors without metastasis were divided into three groups: Mohs group (n = 256), conventional cryopreservation group (n = 130) and experiential resection group (n = 25). The tumor wounds were repaired with adjacent flaps, myocutaneous flaps and free skin grafts or direct suture. All the skin flaps or skin grafts survived in 8 cases with stage 鈪，

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