Q开关755nm翠绿宝石激光治疗131例皮肤色素增加性皮肤病临床分析

发布时间：2018-03-28 00:39

本文选题：Q开关紫翠宝石激光　切入点：色素性疾病　出处：《石河子大学》2017年硕士论文

【摘要】：目的:观察Q开关紫翠宝石激光治疗皮肤色素性疾病的临床疗效与不良反应。方法:选取我院2014年12月至2016年10月收治的131例色素增加性皮肤病(包括雀斑、脂溢性角化、太田痣、蓝黑文身、褐青色痣)患者,其中雀斑54例,脂溢性角化35例,太田痣27例,文身9例,颧部褐青色痣6例,均予以Q开关翠绿宝石激光(755nm波长)治疗,归纳总结其临床治疗效果,分别对各组患者性别、就诊年龄、病程、治疗次数进行回顾分析。对比每次治疗前后的变化以及首次治疗前和末次治疗后3个月的变化,每次治疗间隔约1~3个月,每位患者均随访3~6个月,并记录炎症后色素沉着等不良反应。结果:本组患者不同病种除褐青色痣之外治疗总有效率均在75%以上,褐青色痣治疗总有效率为33.33%;其中雀斑痊愈率88.90%,有效率98.10%,脂溢性角化痊愈率85.71%,有效率94.28%,太田痣痊愈率66.67%,有效率88.90%,文身痊愈率55.56%,有效率77.78%,颧部褐青色痣痊愈率16.67%,有效率33.33%。本研究131例患者的治疗次数分布在1~8次之间,其中太田痣患者组平均治疗次数最多,为6.52±1.28次;其次是文身患者组,为6.33±1.58次,颧部褐青色痣组5.83±1.60,脂溢性角化组2.97±0.95,雀斑组2.57±0.54,经随访调查有19例患者治疗后出现炎症后色沉,大多数炎症后色沉约半年后消退,所有患者治疗中及疗程结束后均无出现感染病例,所有患者均无出现疤痕病例。其中不同疾病患者痊愈率和有效率之间差异经卡方检验有统计学意义(χ2=22.658,P0.05;χ2=29.780,P0.05)。结论:Q开关紫翠宝石激光对雀斑、脂溢性角化、太田痣、文身、治疗效果好,对颧部褐青色痣有一定疗效。
[Abstract]:Objective: to observe the clinical efficacy and adverse reactions of Q-switched Alexandrite laser in the treatment of skin pigmented diseases. Methods: 131 cases of pigmented increased dermatosis (including freckles seborrheic keratosis) from December 2014 to October 2016 were selected. There were 54 cases of freckles, 35 cases of seborrheic keratosis, 27 cases of Ota nevus, 9 cases of tattoo and 6 cases of zygomatic nevus. All patients were treated with Q-switched emerald laser at 755 nm. The results of clinical treatment were summarized, and the sex, age, course and times of treatment were analyzed retrospectively, and the changes before and after the first treatment and 3 months after the last treatment were compared. The interval of treatment was about 1 ~ 3 months, and each patient was followed up for 3 ~ 6 months, and the adverse reactions such as pigmentation after inflammation were recorded. The total effective rate of treatment of nevus was 33.33. The cure rate of freckles was 88.90, the effective rate was 98.10, the cure rate of seborrheic keratosis was 85.71, the effective rate was 94.2828.1, the cure rate of nevus of Ota was 66.67, the effective rate was 88.90, the cure rate of tattoo was 55.56, the effective rate was 77.788.The cure rate of zygomatic nevus was 16.677.67. The treatment frequency of 131 patients in this study ranged from 1 to 8 times. The average times of treatment were 6.52 卤1.28 in nevus of Ota group, 6.33 卤1.58 in tattoo group, 5.83 卤1.60 in zygomatic brown blue nevus group, 2.97 卤0.95 in seborrheic keratosis group and 2.57 卤0.54 in freckle group. Most of the patients disappeared after inflammation after about half a year, and no infection occurred in all patients during treatment and after the course of treatment. There were no scar cases in all the patients. The difference of recovery rate and effective rate among the patients with different diseases was statistically significant by chi-square test (蠂 ~ 2 ~ 2 ~ (22.658) P _ (0.05); 蠂 ~ (2 +) ~ (29. 780) P ~ (0.05)). Conclusion the effect of the Twi-Q switch purple ruby laser on freckles, seborrheic keratosis, nevus of Ota, tattoo, etc. The treatment effect is good, has certain curative effect to the zygomatic part brown blue nevus.
【学位授予单位】：石河子大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R751.05

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