马来酸氟吡汀对带状疱疹后三叉神经痛常规治疗的影响

发布时间：2018-03-28 05:38

本文选题：带状疱疹后三叉神经痛　切入点：马来酸氟吡汀　出处：《中国医科大学学报》2017年07期

【摘要】：目的探讨马来酸氟吡汀对带状疱疹后三叉神经痛常规治疗的影响。方法选取2015年12月至2016年12月期间在本院疼痛门诊就诊的带状疱疹后三叉神经痛患者40例,随机分为观察组与对照组,每组20例。所有入组患者对本研究均知情并签署知情同意书。对照组患者给予口服加巴喷丁和氨酚羟考酮治疗,观察组患者给予口服加巴喷丁、氨酚羟考酮和马来酸氟吡汀治疗。比较2组患者治疗前后视觉模拟评分(VAS)、SF-36量表评分变化情况及临床治疗有效率。结果治疗前2组患者VAS评分及SF-36量表各维度因子评分比较差异均无统计学意义(均P0.05);治疗后2组患者VAS评分与治疗前比较均显著下降(P0.05),观察组的VAS评分显著低于对照组(P0.05);治疗后2组患者SF-36量表各维度因子评分与治疗前比较显著升高(P0.05),观察组SF-36评分均显著高于对照组(P0.05);观察组患者临床治疗有效率高于对照组(P0.05)。结论在常规药物治疗基础上加用马来酸氟吡汀,能够有效提高带状疱疹后三叉神经痛的治疗效果,更好地缓解疼痛,提高患者生活质量。
[Abstract]:Objective to investigate the effect of flupyridine maleate on routine treatment of postherpetic trigeminal neuralgia. Methods Forty patients with postherpetic trigeminal neuralgia were selected from December 2015 to December 2016. All the patients in the study group were informed of the study and signed the informed consent. The patients in the control group were given oral gabapentin and aminophenol hydroxycodone, and the patients in the observation group were given gabapentin orally. The changes of visual analogue score (VAS) and SF-36 scale before and after treatment and the effective rate of clinical treatment were compared between the two groups. Results before the treatment, the VAS score and the SF-36 dimension factors of the two groups were compared. There was no significant difference in the scores between the two groups (all P 0.05), the VAS scores of the two groups decreased significantly after treatment compared with those before treatment, the VAS scores in the observation group were significantly lower than those in the control group (P 0.05), and the scores of each dimension of the SF-36 scale in the two groups after treatment were significantly lower than those in the control group (P 0.05). The SF-36 score of the observation group was significantly higher than that of the control group (P 0.05), the effective rate of clinical treatment in the observation group was higher than that of the control group (P 0.05). It can effectively improve the treatment effect of trigeminal neuralgia after herpes zoster, relieve pain and improve the quality of life of patients.
【作者单位】：中国医科大学附属第一医院疼痛科;
【分类号】：R745.11;R752.12

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