抑郁症状对尖锐湿疣患者生活质量的影响

发布时间：2018-03-29 20:44

  本文选题：尖锐湿疣　切入点：生活质量　出处：《郑州大学》2012年硕士论文

【摘要】：背景与目的 目前,随着生物-心理-医学模式的日趋成熟,心理健康越来越受到人们的关注,心理干预也逐步应用于临床治疗,并取得良好的效果。尖锐湿疣(condyloma acuminata, CA)患者作为一个特殊的人群,其心理问题不容忽视。该病临床增生快,易复发,部分还有发生癌变的可能,患者往往存在不同程度的心理障碍,生活质量普遍下降,抑郁症状在临床较为常见。严重的心理应激与机体的免疫功能存在广泛的交互影响,导致机体免疫功能的低下,进而可促进疣体的复发。本文通过对CA患者的抑郁症状及生活质量进行调查,分析患者抑郁及生活质量的影响因素,并进一步探讨抑郁症状与生活质量之间的关系,为临床实施心理干预,提高患者生活质量和疗效提供理论依据。 方法 2010年3月至2011年6月郑州大学第一附属医院皮肤科门诊治疗的170例CA患者作为研究组,对照组为170例健康者。研究组和对照组均采用Zung抑郁自评量表(self-rating depression scale, SDS)、皮肤科生活质量指数(dermatology life quality index, DLQI)进行问卷调查,并用自制调查表采集一般情况。研究组SDS≥0.5者作为抑郁组,SDS0.5者作为非抑郁组。利用SPSS17.0统计软件对数据进行统计学分析,定性资料的比较采用χ2检验,定量资料的比较采用t检验及单因素方差分析。各相关因素与生活质量的关系采用单因素相关分析和多元回归,检验水准α=0.05。 结果 1.研究组中抑郁的发生率明显高于对照组(47.5%vs26.6%),且抑郁的发生与经济状况、婚姻、病程、对疾病的认识、文化程度、自觉症状、初次就诊情况相关(P0.05),与性别、年龄无关(P0.05)。 2.研究组生活质量总分明显高于对照组(12.72±2.02vs7.83±1.11),且与性别、经济状况、婚姻、病程、对疾病的认识、文化程度、自觉症状、初次就诊情况、抑郁症状相关(P0.05),与年龄无关(P0.05)。 3.抑郁症状与生活质量呈正相关(r=0.718,P0.001),研究组中抑郁组的生活质量总分明显高于非抑郁组(14.35±1.65vs11.31±1.17,t=13.389),且抑郁程度与生活质量总分相关。 结论 1.CA患者抑郁症状发生率高,并导致生活质量下降； 2.经济状况、婚姻、病程、对疾病的认识、文化程度、自觉症状、初次就诊情况等因素均是患者抑郁症状的影响因素,而患者的抑郁症状、婚姻、病程、对疾病的认识及初次就诊情况是生活质量的危险因素。
[Abstract]:Background and purposeAt present, with the maturity of biological-psychological-medical model, people pay more and more attention to mental health. Psychological intervention has been gradually applied to clinical treatment and achieved good results.As a special group, condyloma acuminata (CAA) patients have psychological problems that can not be ignored.The clinical hyperplasia of the disease is fast, easy to recur, and part of the disease has the possibility of canceration. Patients often have different degrees of psychological disorders, the quality of life is generally decreased, and depressive symptoms are more common in clinical practice.Serious psychological stress and immune function of the body have extensive interaction, resulting in low immune function of the body, which can promote the recurrence of warts.By investigating the depression symptoms and quality of life of CA patients, this paper analyzed the influencing factors of depression and quality of life, and further discussed the relationship between depression symptoms and quality of life, so as to carry out psychological intervention in clinic.To improve the quality of life and efficacy of patients to provide theoretical basis.MethodFrom March 2010 to June 2011, 170 CA patients were treated in Department of Dermatology, first affiliated Hospital of Zhengzhou University as study group and 170 healthy persons as control group.Both the study group and the control group were investigated with self-rating depression scale (Zung) and dermatology life quality (DLQI).The study group with SDS 鈮，

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