妊娠合并梅毒母儿健康状况分析

发布时间：2018-04-06 23:27

本文选题：妊娠　切入点：梅毒　出处：《重庆医学》2014年13期

【摘要】：目的探讨妊娠合并梅毒孕妇孕期进行驱梅治疗对妊娠结局的影响。方法 51例经血清学检查确诊为妊娠合并梅毒孕妇,根据孕期是否进行规范的驱梅治疗分为治疗组(38例)和对照组(13例),比较两组孕妇的妊娠结局、围产儿预后以及分娩先天性梅毒儿的情况。结果 (1)妊娠结局:治疗组孕妇足月产率为92.1%,而对照组为30.8%,两组比较差异有统计学意义(P0.05)。治疗组孕妇早产与死胎、流产、死产发生率分别为7.9%和0,明显低于对照组的46.1%和23.1%,两组比较差异有统计学意义(P0.05)。(2)围产儿预后:治疗组孕妇分娩正常新生儿者占84.2%,而对照组占30.0%,两组比较差异有统计学意义(P0.05)。梅毒孕妇开始治疗的时间越早,先天性梅毒患儿的发生率越低(P0.05)。(3)确诊为先天性梅毒儿的有13例,确诊依据临床表现及19S-IgM-TP酶联免疫吸附实验(ELISA)检测结果。结论对妊娠梅毒的孕妇采取规范的驱梅治疗是改善妊娠结局和围产儿预后的关键,早发现、早治疗十分重要。19S-IgM-TP ELISA方法检测对新生儿梅毒治疗疗效的早期判定有临床意义。
[Abstract]:Objective to investigate the effect of pregnancy combined with syphilis on pregnancy outcome.Methods 51 cases of pregnant women with syphilis diagnosed by serological examination were divided into treatment group (n = 38) and control group (n = 13).Perinatal prognosis and delivery of congenital syphilis.Results 1) pregnancy outcome: the full-term delivery rate of pregnant women in the treatment group was 92.1g, while that in the control group was 30.8.The difference between the two groups was statistically significant (P 0.05).In the treatment group, preterm delivery and stillbirth, abortion,13 cases of congenital syphilis were diagnosed as congenital syphilis. The diagnosis was based on clinical manifestation and 19S-IgM-TP Elisa.Conclusion it is the key to improve the outcome of pregnancy and perinatal prognosis for pregnant women with pregnant syphilis. Early detection of early treatment is very important. The detection of early treatment by 19S-IgM-TP ELISA has clinical significance in early judgement of therapeutic effect of neonatal syphilis.
【作者单位】：浙江省乐清市第六人民医院妇产科;浙江省乐清市妇幼保健院儿科;浙江省乐清市妇幼保健院病理科;浙江省乐清市妇幼保健院保健科;
【基金】：温州市卫生局科研基金资助项目(2011B089)
【分类号】：R759.15

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