咽喉部Ⅱ期梅毒21例黏膜损害形态和临床特征分析

发布时间：2018-04-11 23:25

本文选题：梅毒 + 咽喉　；参考：《中国皮肤性病学杂志》2017年01期

【摘要】：目的探讨咽喉部梅毒的鉴别和诊断要点。方法回顾性分析2011年2月-2015年1月在本院耳鼻咽喉科以咽喉症状及咽喉部黏膜损害为特征首诊的21例Ⅱ期梅毒患者的临床资料,包括纤维喉镜检查结果、皮损部位和形态及临床特征等。结果该21例患者主要病损区域均是以扁桃体和软腭为中心的口咽部,累及舌根者8例,伴喉部黏膜受损者5例。病损黏膜均表现为周围伴有红色充血带的黏膜白斑,未发现单独存在黏膜红斑的病例。喉部黏膜均伴有非特异性炎症,其中4例声嘶患者声带充血和肿胀,黏膜呈白斑样增生。抗梅毒治疗的预后均较好。结论咽喉部Ⅱ期梅毒病损区域多为扁桃体和软腭为中心的口咽部,但常伴有喉炎,并可加重声带的机械性损伤。病损主要为黏膜白斑,白斑周围伴潮红色充血带,结合病损局部检查(病理活检和渗出物涂片)和梅毒血清实验室检查可以确诊,青霉素为该病治疗的一线用药。
[Abstract]:Objective to study the differential diagnosis and diagnosis of pharynx and larynx syphilis.Site, morphology and clinical features of skin lesions.Results the main lesion areas of 21 patients were the oropharynx with tonsil and soft palate as the center, including 8 cases with tongue root and 5 cases with laryngeal mucosal damage.Leukoplakia with red hyperemia was found in all the lesions, and there was no single case of erythema.Non-specific inflammation was found in all laryngeal mucosa, including hyperemia and swelling of vocal cord in 4 patients with hoarseness and leukoplakia.The prognosis of anti-syphilis treatment was better.Conclusion the pharyngeal and laryngeal secondary syphilis lesions are mostly tonsil and soft palate centered oropharynx, but often accompanied by laryngitis, and may aggravate the mechanical injury of vocal cord.The lesions were mainly mucosal leukoplakia with damp red hyperemia around the leukoplakia combined with local examination (pathological biopsy and exudate smear) and syphilis serum laboratory examination. Penicillin was the first-line drug for the treatment of the disease.
【作者单位】：中国医科大学附属第一医院耳鼻咽喉科;中国医科大学附属盛京医院;
【分类号】：R759.1

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