局部光动力疗法治疗皮肤恶性肿瘤的远期疗效评价

发布时间：2018-04-14 17:30

本文选题：皮肤恶性肿瘤 + 局部光动力疗法　；参考：《重庆医学》2017年10期

【摘要】：目的评价局部光动力疗法治疗皮肤恶性肿瘤的远期疗效。方法回访2006年2月至2010年2月在该科接受过局部光动力治疗的皮肤恶性肿瘤患者134例,其中基底细胞癌64例、鳞状细胞癌16例、Bowen病28例、湿疹样癌26例,单独采用局部光动力治疗,或者手术联合局部光动力治疗,治疗结束后每间隔6个月至该科门诊临床观察,随访5年,观察肿瘤的复发情况。结果单纯局部光动力治疗组中,基底细胞癌复发6例,鳞状细胞癌复发2例,Bowen病复发4例,湿疹样癌复发9例;手术联合局部光动力治疗组,基底细胞癌复发3例,鳞状细胞癌复发1例,Bowen病复发4例,湿疹样癌复发9例。结论局部光动力学治疗可以明显改善皮肤恶性肿瘤患者的生活质量,控制肿瘤发展,但在减少其复发率方面有待进一步研究。
[Abstract]:Objective to evaluate the long-term effect of local photodynamic therapy on skin malignant tumors.Methods from February 2006 to February 2010, 134 patients with cutaneous malignant tumors received local photodynamic therapy in this department, including 64 cases of basal cell carcinoma, 28 cases of squamous cell carcinoma and 28 cases of Bowen's disease, 26 cases of eczema like carcinoma.Local photodynamic therapy alone or surgery combined with local photodynamic therapy were performed at intervals of 6 months to the outpatient clinic and followed up for 5 years to observe the recurrence of tumor.Results in the local photodynamic therapy group, 6 cases of basal cell carcinoma recurred, 2 cases of squamous cell carcinoma recurred, 9 cases of eczema carcinoma recurred, and 3 cases of basal cell carcinoma recurred after operation combined with local photodynamic therapy.Squamous cell carcinoma recurred in 1 case, Bowen's disease recurred in 4 cases, eczema carcinoma recurred in 9 cases.Conclusion Local photodynamic therapy can significantly improve the quality of life of patients with malignant skin tumors and control the development of tumors, but further research is needed to reduce the recurrence rate.
【作者单位】：第三军医大学大坪医院整形美容科;
【基金】：国家自然科学基金资助项目(81672694)
【分类号】：R739.5

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