表皮样囊肿癌变临床病理分析

发布时间：2018-04-29 22:11

本文选题：表皮囊肿 + 癌　；参考：《天津医药》2014年08期

【摘要】：目的探讨表皮样囊肿癌变的临床特点、病理形态、免疫组化及预后等。方法收集6例表皮样囊肿癌变资料,分析其临床特点,观察病理形态及免疫组化表型,通过随访了解其预后。结果临床表现均为局部包块,行扩大切除,随访1年,无复发和转移。病理检查示为不整形肿块,囊性,内为豆渣样物,镜检示囊内为变性层状角质物,囊壁衬覆鳞状上皮,癌变区鳞状上皮呈巢团状间质浸润。病理诊断表皮样囊肿癌变为鳞状细胞癌。免疫表型:6例癌变鳞状细胞CK5/6、P63阳性。结论表皮样囊肿癌变非常少见,诊断主要靠常规病理切片确诊,免疫组化标记协助诊断,局部适当扩大切除为首选,其恶性程度较低,预后较好。
[Abstract]:Objective to investigate the clinical features, pathological morphology, immunohistochemistry and prognosis of epidermoid cyst carcinogenesis. Methods six cases of epidermoid cysts with carcinogenesis were collected, their clinical features, histopathology and immunohistochemical phenotype were observed. Results all the clinical manifestations were local mass, extended resection, followed up for 1 year, no recurrence or metastasis. Pathological examination showed no plastic mass, cystic and soybean dregs. Microscopic examination showed denatured layered keratinocytes in the capsule, squamous epithelium lining the cystic wall and nestled interstitial infiltration in the cancerous area. Pathological diagnosis of carcinogenesis of epidermoid cyst to squamous cell carcinoma. Immunophenotypes: 6 cases of malignant squamous cell CK5 / 6 p63 positive. Conclusion Carcinogenesis of epidermoid cysts is rare. The diagnosis is mainly confirmed by conventional pathological sections, with the help of immunohistochemical markers, and local excision is the first choice. The malignant degree is lower and the prognosis is better.
【作者单位】：新疆阿克苏市农一师医院病理科;新疆阿克苏市农一师医院理疗科;
【分类号】：R739.5

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