痤疮2号方联合IPL治疗寻常痤疮后红斑临床疗效观察

发布时间：2018-05-05 14:11

本文选题：痤疮2号方 + IPL　；参考：《山东中医药大学》2017年硕士论文

【摘要】：目的:观察口服中药痤疮2号方联合IPL治疗寻常痤疮后红斑的临床疗效,为寻常痤疮后红斑寻求一种疗效好、副作用少、复发率低的治疗新方法。方法:随机选取74例门诊病例,治疗组37例,给予口服中药痤疮2号方联合IPL治疗,对照组37例,仅应用IPL治疗仪治疗。首次治疗前(第1天)、第三次治疗前(第28天)和末次治疗2周后(第56天)分别拍照记录,根据红斑颜色、数量、大小、分布情况做出红斑综合积分评定,并以红斑综合积分减少率作为疗效指数评定临床疗效。结果:以第56天评定结果作为最终结果,治疗组和对照组的痊愈率分别为37.8%和16.2%,愈显率分别为83.3%和54.1%,总有效率分别是100%和83.8%,两组比较差异有统计学意义(P0.05),治疗组在红斑颜色、数量、大小方面的疗效均优于对照组。治疗组和对照组不良反应出现的概率分别为5.41%和13.51%,两组比较差异无统计学意义(P0.05),提示两组不良反应无差异。治疗组和对照组的复发率分别为14.29%和66.67%,两组比较差异有统计学意义(P0.05),提示治疗组复发率低。结论:口服中药痤疮2号方联合IPL治疗寻常痤疮后红斑疗效确切,副作用少,复发率低,使患者恢复自信,进而提高身心健康和生活质量,体现了中医中药的特色和优势,值得进一步推广。
[Abstract]:Objective: to observe the clinical effect of Acne No.2 prescription combined with IPL in the treatment of erythema vulgaris after acne vulgaris, and to seek a new method for treating Erythema vulgaris with good curative effect, less side effect and low recurrence rate. Methods: a total of 74 outpatients were randomly selected as treatment group (n = 37) and treated with traditional Chinese medicine acne prescription No. 2 combined with IPL. The control group (n = 37) was treated with IPL only. Before the first day of treatment (day 1), before the third treatment (day 28) and 2 weeks after the last treatment (day 56), they were photographed and evaluated according to the color, quantity, size and distribution of erythema. The reduction rate of erythema integral was used as the curative effect index to evaluate the clinical curative effect. Results: the cure rates of the treatment group and the control group were 37.8% and 16.2%, respectively, and the effective rates were 83.3% and 54.1%, respectively. The total effective rates were 100% and 83.8%, respectively. The difference between the two groups was statistically significant (P 0.05). The effect of quantity and size was better than that of control group. The probability of adverse reactions in the treatment group and the control group were 5.41% and 13.51%, respectively. There was no significant difference between the two groups (P 0.05), indicating that there was no difference in the adverse reactions between the two groups. The recurrence rates of the treatment group and the control group were 14.29% and 66.67%, respectively. The difference between the two groups was statistically significant (P 0.05), indicating that the recurrence rate of the treatment group was low. Conclusion: the treatment of erythema after acne vulgaris by oral acne prescription No. 2 and IPL is effective, with less side effects and low recurrence rate, which can restore the confidence of the patients, improve the physical and mental health and the quality of life, and reflect the characteristics and advantages of traditional Chinese medicine in the treatment of erythema vulgaris. It is worth further popularizing.
【学位授予单位】：山东中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R758.733

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