妇产科139401例患者梅毒血清学抗体检测结果统计分析

发布时间：2018-05-06 12:22

本文选题：梅毒 + 孕妇　；参考：《中国皮肤性病学杂志》2017年07期

【摘要】：目的了解妇产科患者梅毒感染情况,为女性梅毒的防治尤其是孕产妇梅毒防治工作提供参考依据。方法选取2011-2015年天津市中心妇产科医院就诊的女性患者139 401例作为研究对象(不含新生儿),用酶联免疫吸附试验(ELISA)进行血清梅毒抗体筛查,阳性者用梅毒螺旋体抗体明胶凝集试验(TPPA)进行确证,两者均为阳性者认为梅毒血清学阳性,通过快速血浆反应素试验(RPR)检测其效价。对不同年度、不同年龄段和科室梅毒检测结果进行统计分析。结果共检出阳性患者1 197例,阳性率0.86%,阳性患者中TPPA阳性RPR效价阴性者占53.13%,RPR高滴度患者主要为21~30岁年龄组。妇瘤科检出率最高,产科最低。≤20岁年龄组检出率最高。近五年本院梅毒阳性检出率依次为0.80%,0.87%,0.82%,0.80%和1.00%,2011-2014年梅毒阳性检出率基本相近,2015年明显升高,与前4年相比差异有统计学意义(χ~2=8.745,P0.01)。结论梅毒血清学阳性患者各科室均有检出,且有年轻化趋势,2015年产科梅毒检出率显著升高,加强年轻女性特别是孕妇梅毒筛查有利于降低梅毒垂直传播风险,进而控制梅毒传播。
[Abstract]:Objective to understand the situation of syphilis infection in obstetrics and Gynecology, and to provide reference for the prevention and control of syphilis, especially for pregnant and parturient women. Methods 139401 female patients who had been diagnosed in Tianjin Central Obstetrics and Gynecology Hospital for 2011-2015 years were selected as the research object (without newborn), and the sera syphilis was carried out by enzyme linked immunosorbent assay (ELISA). Antibody screening, positive patients were confirmed with Treponema pallidum gelatin agglutination test (TPPA). Both were positive for syphilis positive, and the titer was detected by rapid plasma reactivity test (RPR). The results of syphilis detection in different years, different ages and departments were statistically analyzed. 1197 cases of positive patients were detected. The positive rate was 0.86%, the positive TPPA positive RPR titer was 53.13%, the RPR high titer was mainly in the 21~30 age group. The detection rate of the gynecoma was the highest, the obstetrics was the lowest. The positive rate of the age group was the highest in the age group. The positive rate of syphilis in the hospital was 0.80%, 0.87%, 0.82%, 0.80% and 1%, and the positive rate of syphilis positive in 2011-2014 years. The difference between 2015 and the previous 4 years was statistically significant (x ~2=8.745, P0.01). Conclusion the positive rate of syphilis in all departments of Syphilis Serological patients has been detected, and the prevalence of syphilis in obstetrics is significantly higher in 2015. Control the spread of syphilis.

【作者单位】：天津市中心妇产科医院检验科;
【分类号】：R446.6;R759.1

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