胶体32磷酸铬联合小剂量地塞米松瘤体内注射治疗小儿皮肤海绵状和混合型血管瘤

发布时间：2018-05-08 19:43

本文选题：磷酸铬- + 地塞米松　；参考：《中山大学学报(医学科学版)》2016年04期

【摘要】：【目的】观察胶体32磷酸铬联合小剂量地塞米松瘤体内注射治疗小儿皮肤海绵状血管瘤或/和混合型血管瘤的疗效。【方法】638例皮肤海绵状血管瘤或/和混合型血管瘤,共计778个皮损分别接受1~3个疗程32磷酸铬联合地塞米松瘤体内注射治疗,平均注射剂量为(673±275)k Bq/cm2,混合型血管瘤皮损辅助32磷敷贴治疗,根据血管瘤大小及患者年龄评价治疗效果。【结果】1平均疗程1.59个,按瘤体面积判定:1~3个疗程的累计治愈率分别为64.27%、89.08%和96.14%,累计有效率分别为91.90%、97.17%和98.07%。瘤体越小,其治疗效果越好,差异均有统计学意义(P均0.001)。2按患儿年龄判定:1~3个疗程患儿的累计治愈率分别为62.70%、88.25%和94.67%,累计有效率分为别为89.66%、96.08%和98.12%。年龄越小,效果越明显,各疗程差异均有统计学意义(P均0.001)。【结论】胶体32磷酸铬联合小剂量地塞米松瘤体内注射是一种治疗小儿皮肤海绵状血管瘤/混合型血管瘤安全有效且操作简便的方法,值得临床选用。
[Abstract]:[objective] to observe the efficacy of colloidal chromium 32 phosphate combined with low dose dexamethasone injection in the treatment of skin cavernous hemangioma or / and mixed hemangioma in children. [methods] 638 cases of skin cavernous hemangioma or / and mixed hemangioma were treated. A total of 778 lesions were treated with intratumoral injection of chromium 32 phosphate combined with dexamethasone for 1 ~ 3 courses. The average injection dose was 673 卤275kBq / cm ~ (-2). According to the size of hemangioma and the age of the patients, the curative effect was evaluated. [results] 1 the average course of treatment was 1.59. The cumulative cure rates of 1 ~ 3 courses of treatment were 64.278.08% and 96.14%, respectively. The cumulative effective rates were 91.90% and 98.07%, respectively. The smaller the tumor was, the better the therapeutic effect was. The difference was statistically significant (P < 0.001). The cumulative cure rate was 62.70%, 88.25% and 94.67%, respectively. The cumulative effective rate was 89.66% and 98.12%, respectively. The younger the age, the more obvious the effect. [conclusion] Colloidal chromium 32 phosphate combined with low dose dexamethasone injection is a safe, effective and simple method for the treatment of skin cavernous hemangioma / mixed hemangioma in children. It is worthy of clinical selection.
【作者单位】：中山大学孙逸仙纪念医院核医学科;
【分类号】：R739.5

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