1-12月龄婴儿特应性皮炎发病相关因素分析

发布时间：2018-05-15 00:30

  本文选题：婴儿 + 特应性皮炎　； 参考：《辽宁中医药大学》2016年硕士论文

【摘要】：目的:探讨1-12月龄特应性皮炎(AD)婴儿发病的相关因素,为预防和控制AD提供临床依据。材料与方法:选取2015年1月至2016年1月在解放军第202医院过敏反应科门诊就诊的1-12月龄AD婴儿126例纳入研究组,同一时期在幼儿保健科随机选取1-12月龄健康婴儿142例纳入对照组。本次研究通过填写调查问卷的方式进行,对家族史、母亲妊娠年龄、生产方式、喂养方式、添加辅食时间、室内吸烟、饲养宠物情况7个因素进行卡方检验,分析AD发病的相关因素,对相关因素进行多因素Logistic回归分析,分析各因素与AD发病的相关性。结果:1.研究组126例特应性皮炎患儿,其中男婴71例,占56.35%,女婴55例,占43.65%;对照组142例健康婴儿,其中男婴79例,占55.63%,女婴63例,占44.37%。经卡方检验χ2=0.014,P=0.906,在性别上两组之间没有统计学差异。2.在相关因素分析中,研究自身因素与AD发病的关系,经卡方检验家族史χ2=35.165,P=0.000,母亲妊娠年龄χ2=0.003,P=0.959,生产方式χ2=28.711,P=0.000,喂养方式χ2=7.436,P=0.024,添加辅食时间χ2=0.212,P=0.645,其中家族史、生产方式、喂养方式有统计学意义。3.研究环境因素与AD发病的关系,经卡方检验吸烟环境χ2=11.955,P=0.001,饲养宠物χ2=6.080,P=0.014,吸烟环境和饲养宠物有统计学意义。4.对相关因素进行多因素Logistic回归分析,结果表明家族史(OR=7.105)和生产方式(0R=6.771)与AD发病相关性最强。结论:1.自身因素中家族史、生产方式、喂养方式为1-12月龄婴儿AD发病的相关因素。2.环境因素中吸烟环境、饲养宠物为1-12月龄婴儿AD发病的相关因素。3.家族史和生产方式为1-12月龄婴儿AD发病的主要相关因素。
[Abstract]:Objective: to investigate the risk factors of AD in infants aged from 1 to 12 months old, and to provide clinical basis for prevention and control of AD. Materials and methods: 126 AD infants aged from 1 to 12 months from January 2015 to January 2016 were enrolled in the study group. In the same period, 142 healthy infants aged 1 to 12 months were randomly selected into the control group. This study was conducted by filling out a questionnaire to examine seven factors, including family history, maternal pregnancy age, mode of production, feeding method, supplementary feeding time, indoor smoking, pet keeping, etc. The related factors of AD were analyzed, and multivariate Logistic regression analysis was carried out to analyze the correlation between each factor and AD. The result is 1: 1. There were 126 cases of atopic dermatitis in the study group, including 71 cases of male infants (56.35%), 55 cases of female infants (43.65%), 142 cases of healthy infants in control group, 79 cases of male infants (55.63%) and 63 cases of female infants (44.37%). The chi-square test showed that there was no statistical difference between the two groups. In the analysis of related factors, the authors studied the relationship between their own factors and the incidence of AD. By chi-square test, the family history was 蠂 2 235. 165% P0. 000, the maternal gestational age 蠂 2 0. 003 + P0. 959, the mode of production 蠂 228. 711 P0. 000, the feeding mode 蠂 2 + 7. 436 P0. 024, and the supplementary feeding time 蠂 2 + 0. 212 P0. 645. Among them, the family history, the production mode, the mode of production, Feeding mode has statistical significance. In order to study the relationship between environmental factors and AD, the smoking environment 蠂 ~ 2 ~ 2 ~ (11) 95 ~ (5) P ~ + 0.001, and keeping pets 蠂 ~ (2) 6.080 (P ~ (0.014) were tested by chi-square test. There was statistically significant difference between smoking environment and keeping pets (P ~ (0.014). Multivariate Logistic regression analysis showed that the family history was 7.105) and the mode of production was 6.771). Conclusion 1. The family history, mode of production and feeding mode were related factors of AD in infants aged 1 to 12 months. Among the environmental factors, smoking and keeping pets were related factors of AD incidence in infants aged 1 to 12 months. Family history and mode of production were the main related factors of AD in infants aged 1-12 months.
【学位授予单位】：辽宁中医药大学
【学位级别】：硕士
【学位授予年份】：2016
【分类号】：R758.2
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本文编号：1890171