儿童荨麻疹与成人荨麻疹患者临床特征的比较分析

发布时间：2018-05-19 12:17

本文选题：荨麻疹 + 临床特征　；参考：《中国当代儿科杂志》2017年07期

【摘要】：目的探讨儿童荨麻疹和成人荨麻疹临床特征的差异,为儿童荨麻疹的病因、病情评估及治疗提供参考依据。方法收集2013年1月至2017年5月在中南大学湘雅医院皮肤科就诊的2 411例荨麻疹患者资料进行社会人口学特征分析,并对其中获得完整随访资料的740例荨麻疹患者进行儿童(68例)和成人(672例)荨麻疹临床特征的比较分析。结果儿童组中急性荨麻疹314例,占76.4%(314/411),而成人组以慢性自发性荨麻疹为主(44.8%,896/2 000)。儿童急性荨麻疹以感染为病因者占41%(16/39)。儿童急性荨麻疹的伴随症状以腹痛/腹泻为主(44%,17/39),而成人急性荨麻疹以胸闷/气促为主要伴随症状(32%,11/34)。儿童组慢性荨麻疹治疗前后疾病严重度评分低于成人组(P0.05);儿童组第二代抗组胺药治疗有效率高于成人组(82.1%vs 62.2%,P0.05)。儿童组荨麻疹个人史及家族史阳性率均高于成人组(P0.05)。结论儿童荨麻疹中以急性荨麻疹多见,主要伴随症状为腹痛/腹泻,与成人不同。儿童慢性荨麻疹的疗效较成人佳。儿童急性荨麻疹患者常见病因为感染。具有特应性体质儿童可能易患荨麻疹。
[Abstract]:Objective to explore the difference of clinical features between children urticaria and adult urticaria, and to provide reference for etiology, evaluation and treatment of children urticaria. Methods from January 2013 to May 2017, data of 2 411 patients with urticaria were collected from Department of Dermatology, Xiangya Hospital, Central South University. The clinical features of 740 patients with urticaria were compared with 672 adults and 68 children with urticaria. Results there were 314 cases of acute urticaria in the children group, accounting for 76.4% 314% 411%, while the adult group consisted mainly of chronic spontaneous urticaria (44.8%). Infection was the cause of acute urticaria in children. The associated symptoms of acute urticaria in children were mainly abdominal pain / diarrhea (44 / 39), while in adults acute urticaria was associated with chest tightness / shortness of breath. The score of disease severity before and after treatment of chronic urticaria in children group was lower than that in adult group, and the effective rate of second generation antihistamine therapy in children group was higher than that in adult group (82.1 vs 62.2% P0.05). The positive rates of individual history and family history of urticaria in children group were higher than those in adult group (P 0.05). Conclusion Acute urticaria is common in children with abdominal pain / diarrhea, which is different from adult urticaria. The effect of chronic urticaria in children is better than that in adults. Children with acute urticaria often suffer from infection. Children with atopic constitution may be susceptible to urticaria.
【作者单位】：中南大学湘雅医院皮肤科;
【基金】：国家自然科学基金(81673065) 湖南省自然科学基金(2016JJ3170) 湖南省科技计划项目(2014SK3108)
【分类号】：R758.24

【相似文献】