强脉冲光治疗面部光老化的临床研究

发布时间：2018-05-21 13:40

本文选题：半脸 + 强脉冲光　；参考：《首都医科大学》2010年硕士论文

【摘要】： 目的:皮肤光老化是皮肤长期受到日光照射所引起的损害,表现为皱纹、皮肤粗糙、干燥、松弛、不规则色素改变、毛细血管扩张,甚至可以发生良性或恶性肿瘤。强脉冲光(iniensePulsedllght,IPL)技术作为新一代非剥脱性皮肤美容术,在治疗光老化方面具有很大优势。本课题旨在研究调整强脉冲光治疗光老化的治疗间隔及治疗剂量,研究其是否对治疗效果产生影响。方法:采用科医人公司的Lumenis One激光治疗仪IPL治疗头对20例符合光老化诊断标准且左右面部皮损相对对称女性受试者进行治疗,治疗时受试者左右面部分为4次治疗侧、8次治疗侧,采用每3周1次共4次相对大剂量及每周1次共8次相对小剂量的治疗,并分别于治疗后1月评价效果。结果:根据治疗前与治疗后1月照片对比发现,经治疗面部双侧皮损均有消退,受试者满意率两侧均达70%;医生根据前后照片比较发现两侧皮损消退均在80%以上,且无统计学差异。受试者满意度4次治疗侧非常满意7例,满意7例,一般5例,不满意1例, 8次治疗侧非常满意8例,满意6例,一般5例,不满意1例,经统计学分析,P0.05,差异无统计学意义。与治疗前相比,4次/8次治疗侧面部角质层含水量均无统计学差异结论:强脉冲光治疗光老化效果好,降低治疗剂量、缩短治疗间隔、增加治疗次数后仍可达到理想结果,且起效较快。
[Abstract]:Objective: skin photoaging is a kind of skin damage caused by sunlight irradiation for a long time. It is characterized by wrinkles, rough skin, dry, loose, irregular pigmentation, capillary dilatation and even benign or malignant tumor. As a new generation of non-exfoliative skin beauty surgery, strong pulse light pulse lasing (IPL) technique has great advantages in the treatment of photoaging. The aim of this study was to study the effects of intense pulse light on the treatment of photoaging by adjusting the therapeutic interval and dose. Methods: 20 female subjects who met the diagnostic criteria of photoaging and left and right facial skin lesions were treated with Lumenis One laser therapy instrument IPL. The left and right faces of the subjects were divided into four sides of treatment and eight times of treatment. The patients were treated with four relatively large doses once every 3 weeks and eight relatively low doses once a week, and the effects were evaluated at 1 month after treatment. Results: according to the contrast of photos before and after treatment, the bilateral skin lesions of both sides of the treated face were abated, and the satisfaction rate of both sides of the patients reached 70%, and the doctors found that the bilateral skin lesions disappeared more than 80% according to the comparison of the images before and after treatment. There was no statistical difference. There were 7 cases of satisfaction, 7 cases of satisfaction, 5 cases of general, 1 case of unsatisfactory, 8 cases of satisfaction, 6 cases of satisfaction, 5 cases of average, 1 case of unsatisfactory, 8 times of treatment, 6 cases of satisfaction, 5 cases of general, 1 case of unsatisfactory. The difference was not statistically significant (P 0.05). There was no significant difference in water content in lateral keratinocytes between 4 times / 8 times treatment and before treatment. Conclusion: strong pulse light therapy has good effect on photoaging, reduces treatment dose, shortens treatment interval, and still achieves ideal results after increasing treatment times. And the effect is faster.
【学位授予单位】：首都医科大学
【学位级别】：硕士
【学位授予年份】：2010
【分类号】：R758.1

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