血清降钙素原对炎症性皮肤病患者伴细菌感染的早期鉴别诊断意义

发布时间：2018-05-21 15:52

本文选题：血清降钙素原 + 炎症性皮肤病　；参考：《河北医药》2017年20期

【摘要】：目的探讨血清降钙素原(PCT)对炎症性皮肤病患者伴细菌感染的诊断价值,为早期应用抗生素提供依据。方法选取2015年7月至2016年9月资料完整的76例炎症性皮肤病患者为研究对象,根据临床表现、实验室检查、病原学检测将患者分为细菌感染组和非感染组,所有患者进行血清PCT、C-反应蛋白(CRP)、白细胞计数(WBC)检查。结果细菌感染组患者PCT与非感染组患者PCT相比较,差异有统计学意义(U=-6.083,P0.05),细菌感染组患者CRP与非感染组患者CRP相比较,差异有统计学意义(U=-3.594,P0.05),细菌感染组患者WBC与非感染组患者WBC相比较,差异无统计学意义(U=-0.437,P0.05)。PCT、CRP、WBC的ROC曲线面积分别为0.906、0.740、0.529,PCT、CRP和WBC的灵敏度分别为80.0%、77.5%、47.5%,PCT、CRP和WBC的特异度分别为83.3%、61.1%、69.4%,差异有统计学意义(P0.05)。结论选血清PCT有利于炎症性皮肤病伴感染的鉴别诊断,值得临床参考。
[Abstract]:Objective to investigate the value of serum procalcitonin (PCT) in the diagnosis of bacterial infection in patients with inflammatory dermatosis and to provide evidence for the early application of antibiotics. Methods from July 2015 to September 2016, 76 patients with inflammatory dermatosis were divided into bacterial infection group and non-infection group according to clinical manifestation, laboratory examination and etiology test. All patients were examined with serum PCT-C-reactive protein (CRP) and white blood cell count (WBC). Results there was a significant difference in PCT between bacterial infection group and non-infection group (P 0.05). The CRP of bacterial infection group was higher than that of non-infection group (P 0.05), and that of bacterial infection group was higher than that of non-infection group (P 0.05). There was no significant difference in the area of ROC curve between the bacterial infection group and the non-infection group. The area of the ROC curve was 0.9060.7040 ~ 0.529PCTT and the sensitivity of WBC was 80.077.57.5. the specificity of WBC and WBC were 83.31.1and 83.31.1respectively. Conclusion Serum PCT is helpful to the differential diagnosis of inflammatory dermatosis with infection and is worthy of clinical reference.
【作者单位】：河北医科大学第二医院皮肤性病科;
【基金】：河北省卫生厅科研指导计划(编号:20110372)
【分类号】：R751

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