消痤汤联合美满霉素治疗痤疮疗效观察

发布时间：2018-05-31 16:46

本文选题：消痤汤 + 美满霉素　；参考：《山东医药》2015年02期

【摘要】：目的探讨消痤汤联合美满霉素治疗痤疮的临床疗效。方法将98例寻常型痤疮患者随机分为观察组和对照组各49例,两组均口服美满霉素50 mg/次,2次/d;观察组在此基础上口服消痤汤(100 m L/剂)1剂/d,2次/d。治疗6周后比较两组中医证候积分、生存质量评分及治疗总有效率;随访1个月观察复发情况。结果治疗6周两组症状积分低于治疗前,且观察组低于对照组(P均0.05);两组生存质量评分高于治疗前,且观察组高于对照组(P均0.05)。观察组总有效率明显高于对照组(P0.05)。观察组发生食欲轻度下降3例,对照组发生胃部轻度不适4例,均未影响继续治疗。两组均未出现皮疹、瘙痒等不良反应。观察组复发率明显低于对照组(P0.05)。结论消痤汤联合美满霉素治疗寻常型痤疮效果确切,可降低复发率,效果优于单用美满霉素。
[Abstract]:Objective to explore the clinical effect of Xiaocuo decoction combined with minocycline in the treatment of acne. Methods 98 patients with acne vulgaris were randomly divided into two groups: the observation group (n = 49) and the control group (n = 49). After 6 weeks of treatment, the TCM syndromes score, quality of life score and total effective rate of treatment were compared between the two groups, and the recurrence was observed after 1 month follow up. Results at 6 weeks after treatment, the symptom score of the two groups was lower than that before treatment, and that of the observation group was lower than that of the control group (P < 0.05), and the quality of life score of the two groups was higher than that of the control group (P < 0.05). The total effective rate in the observation group was significantly higher than that in the control group (P 0.05). There were 3 cases of mild loss of appetite in the observation group and 4 cases of mild stomach discomfort in the control group. No rash, pruritus and other adverse reactions were found in both groups. The recurrence rate in the observation group was significantly lower than that in the control group (P 0.05). Conclusion Xiaocuo decoction combined with minocycline is more effective than minocycline in the treatment of acne vulgaris.
【作者单位】：河北联合大学附属医疗集团唐山煤医整形美容医院;河北联合大学附属医院;
【分类号】：R758.733

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