反应性穿通性胶原病3例及文献复习

发布时间：2018-06-04 02:36

本文选题：胶原病 + 穿通性　；参考：《中国皮肤性病学杂志》2017年07期

【摘要】：3例患者均为中老年男性,皮疹多泛发全身或仅累及双下肢,合并2型糖尿病、乙肝小三阳、高血压、高血脂、肾功能衰竭等疾病。临床均表现为丘疹、结节,中央可见脐状凹陷,内填充角栓。组织病理检查示表皮呈杯形下陷,下方为坏死变性的胶原和白细胞碎屑,坏死胶原从表皮穿出。诊断:反应性穿通性胶原病。给予阿维A、沙利度胺、火把花根等药物或(和)抗生素软膏外用治疗后有效。
[Abstract]:All the 3 cases were middle and old men, with generalized skin rash in both lower limbs, type 2 diabetes, hepatitis B, high blood pressure, hyperlipidemia, renal failure and other diseases. The clinical manifestations were papules, nodules, umbilical cavities in the center and horn plugs filled in. Histopathological examination showed that the epidermis was goblet-shaped, with necrotic collagen and leucocyte debris below, and necrotic collagen perforated from the epidermis. Diagnosis: reactive penetrating collagen disease. Avera, thalidomide, torch root and other drugs or / and antibiotic ointment are effective after external treatment.
【作者单位】：重庆市第一人民医院皮肤科;
【基金】：重庆市科委技术研发平台专项“重庆市皮肤病临床医学研究中心”建设项目(cstc2015yfpt-gcjsyjzx120014)
【分类号】：R758.6

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