棘层松解浸润性原发性乳房外Paget病

发布时间：2018-06-15 10:56

  本文选题：乳房外Paget病 + 棘层松解性　； 参考：《临床皮肤科杂志》2017年09期

【摘要】：报告1例棘层松解浸润性原发性乳房外Paget病。患者男,66岁。会阴红斑溃疡10余年。皮肤科检查:阴茎、阴囊及阴阜大片红斑及溃疡,其上有大小不等的结节及大量脓性分泌物。皮损组织病理:表皮棘层明显增生肥厚,向真皮内浸润,细胞排列絮乱,异形明显,可见核分裂象及角化不良细胞,真皮内可见少量鳞状细胞团块,周围大量炎性细胞浸润。腹股沟淋巴结组织病理:淋巴结内见Paget样细胞浸润。诊断:棘层松解浸润性原发性乳房外Paget病。
[Abstract]:A case of invasive primary extramammary Paget disease was reported. The patient was 66 years old. Perineum erythema ulcer more than 10 years. Dermatology: large erythema and ulcers of penis, scrotum and caruncle, with various sizes of nodules and massive purulent secretions. Histopathology of lesions: epidermal spinous layer obviously proliferated and thickened, infiltrated into dermis, cells arranged in disorder, abnormal shape, mitotic and keratosis cells could be seen, a small amount of squamous cell mass could be seen in dermis, and a large number of inflammatory cells were infiltrated around the dermis. Inguinal lymph node histopathology: Paget-like cell infiltration was seen in the lymph node. Diagnosis: invasive primary extramammary Paget disease.
【作者单位】： 昆明医科大学第二附属医院皮肤科;
【分类号】：R739.5

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