二期梅毒合并人免疫缺陷病毒感染42例

发布时间：2018-06-21 20:36

本文选题：HIV + 二期梅毒　；参考：《实用医学杂志》2014年15期

【摘要】：目的:总结二期梅毒合并人免疫缺陷病毒(HIV)感染的临床特点和高效抗逆转录病毒治疗(HAART)对驱梅治疗后血清转归的影响。方法 :对42例二期梅毒合并HIV感染者进行病史资料采集、临床体格检查和实验室检查,分析其流行病学特点、临床皮疹特征和治疗后血清滴度的变化。结果:二期梅毒合并HIV感染传播方式均为性接触传播,男男同性传播有27例(27/42,64.3%),为主要感染方式。临床表现以躯干四肢皮肤玫瑰疹为主,共有30例(30/42,71.4%)。接受HAART治疗的11例患者血浆反应素环状卡片试验(RPR)滴度下降快于未接受HAART治疗的31例患者。结论:男男同性恋人群为二期梅毒合并HIV感染高危人群,二期梅毒皮疹形态多种多样,同时接受HAART治疗有利于梅毒RPR滴度的降低。
[Abstract]:Objective: to summarize the clinical characteristics of secondary syphilis complicated with human immunodeficiency virus (HIV) infection and the effect of HAART on serum outcome after treatment. Methods: 42 cases of secondary syphilis complicated with HIV infection were collected, clinical physical examination and laboratory examination were performed to analyze the epidemiological characteristics, clinical rash characteristics and changes of serum titer after treatment. Results: the modes of transmission of secondary syphilis complicated with HIV infection were all sexual contact transmission, 27 cases of male homosexual transmission were 27 / 42 / 64.3%, which were the main way of infection. The clinical manifestations were mainly roseola of trunk and extremities. There were 30 cases with 30% and 42% 71.4%. The RPRs of plasma RPRs in 11 patients treated with HAART decreased more rapidly than those in 31 patients without HAART. Conclusion: male homosexuals are high risk group of secondary syphilis complicated with HIV infection. Secondary syphilis rash has a variety of forms. At the same time, HAART treatment is beneficial to decrease the RPR titer of syphilis.
【作者单位】：广州市第八人民医院皮肤性病科;
【基金】：广东省科技计划项目(编号:2012B031800332) 广州市卫生局科研课题项目(编号:20121A011079)
【分类号】：R759.1

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