糖皮质类固醇激素在带状疱疹治疗中的疗效评价

发布时间：2018-07-09 13:05

本文选题：带状疱疹 + 糖皮质类固醇激素　；参考：《浙江大学》2010年硕士论文

【摘要】： 目的：评价糖皮质类固醇激素对带状疱疹急性疼痛、局部水肿及皮损的治疗效果,为带状疱疹治疗中合理应用糖皮质类固醇激素提供一定的指导作用。方法：选取邵逸夫医院皮肤科2008至2009期间收治入院的带状疱疹48例,所有患者均接受相同的抗病毒和止痛及营养神经治疗。选取其中24例在治疗过程中使用糖皮质类固醇激素的患者作为糖皮质类固醇激素应用组,24例在治疗过程中未使用糖皮质类固醇激素的患者作为对照组。观察糖皮质类固醇激素应用组中局部肿胀消退情况,分析两组患者疼痛缓解及水疱干涸结痂所需天数是否有显著性差异,以评价糖皮质类固醇激素在带状疱疹治疗中的疗效。结果：糖皮质类固醇激素应用组患者疼痛缓解及水疱干涸结痂所需时间明显缩短,与对照组相比有统计学差异(P0.05),糖皮质类固醇激素应用组中的病例局部肿胀迅速消退。结论：在带状疱疹的治疗中,合理应用中等剂量糖皮质类固醇激素可有效缓解病人急性疼痛和局部肿胀,加速皮损结痂愈合。
[Abstract]:Objective: to evaluate the therapeutic effect of glucocorticoid on acute pain, local edema and lesions of herpes zoster, and to provide guidance for the rational use of glucocorticoid in herpes zoster treatment. Methods: 48 patients with herpes zoster admitted from 2008 to 2009 in Dermatology Department of Shaw Hospital were treated with the same antiviral and analgesic and nutritional nerve therapy. Twenty-four patients who were treated with glucocorticoid were selected as the control group and 24 patients who did not use glucocorticoid during the course of treatment were selected as the control group. To evaluate the curative effect of glucocorticoid on herpes zoster, we observed the local swelling and subsided in the glucocorticoid treatment group, and analyzed whether there was significant difference between the two groups in pain relief and blisters drying up scabbing, in order to evaluate the curative effect of glucocorticoid on herpes zoster. Results: in the glucocorticoid treatment group, the time of pain relief and blister drying up scab was significantly shortened. Compared with the control group, there was a statistical difference (P0.05), glucocorticoid treatment group in the case of local swelling quickly dissipated. Conclusion: in the treatment of herpes zoster, moderate dose of glucocorticoid can effectively relieve the acute pain and local swelling and accelerate the healing of scab.
【学位授予单位】：浙江大学
【学位级别】：硕士
【学位授予年份】：2010
【分类号】：R752.12

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