银屑病治疗现状及进展

发布时间：2018-08-27 07:04

【摘要】：银屑病是一种常见的慢性炎性皮肤病，具有明显复发性。常见皮损表现为覆有层层银白色鳞屑的红斑、丘疹，皮损境界清晰，鳞屑堆积可高出皮面，伴有明显瘙痒。以青壮年的头皮、四肢关节伸侧多见，亦可泛发于全身皮肤，寻常型系统损害较少。银屑病在世界范围内分布，病因尚不明确，已经证实，银屑病是一种多基因遗传病，免疫介导是其主要的发生机制，诱发因素复杂多样，病情容易反复，临床上仅能对症治疗，多采用综合治疗的手段，以达到迅速改善患者症状、减少复发次数及延长复发间隔的治疗目的。目前用于治疗银屑病的方法多种多样，包括各种外用治疗、全身治疗及物理治疗，以及近年来发展迅速的生物制剂疗法。本文就上述治疗方法及其优缺点、注意事项等进行简要介绍。
[Abstract]:Psoriasis is a common chronic inflammatory skin disease with obvious relapse. The common lesions were erythema and papules covered with layers of silvery white scales. Young scalp, limb joint extension is more common, can also be generalized to the skin, less damage to the common system. Psoriasis is distributed all over the world. The etiology of psoriasis is not clear yet. It has been proved that psoriasis is a polygenic hereditary disease, immune mediating is the main mechanism of psoriasis, the inducing factors are complex, the disease is easy to repeat, and the disease can only be treated clinically. In order to improve the symptoms, reduce the number of recurrence and prolong the recurrence interval, comprehensive therapy was used to improve the symptoms of the patients. At present, there are a variety of treatments for psoriasis, including external therapy, systemic therapy and physical therapy, as well as the rapid development of biological agent therapy in recent years. This article briefly introduces the above treatment methods, their advantages and disadvantages, matters needing attention and so on.
【学位授予单位】：重庆医科大学
【学位级别】：硕士
【学位授予年份】：2013
【分类号】：R758.63

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