牛奶蛋白过敏所致婴儿湿疹的早期识别及干预效果

发布时间：2018-10-05 08:13

【摘要】：目的探讨牛奶蛋白过敏和婴儿湿疹的关系,研究牛奶蛋白过敏早期识别及早期回避对婴儿湿疹的作用。方法 241例婴儿湿疹患儿分为观察组(n=161)及对照组(n=80),观察组再分为A、B、C组,A组纯母乳喂养儿母亲回避牛奶及其制品,B组人工喂养儿给予氨基酸配方奶或深度水解蛋白配方奶喂养,C组混合喂养儿母亲回避牛奶制品及添加氨基酸配方奶或深度水解蛋白配方奶喂养,对照组患儿进食普通配方奶粉或(和)母亲不能回避牛奶制品。于生后6个月内随访观察婴儿皮损情况。结果 6月龄时观察组婴儿湿疹的总有效率高于对照组,差异有统计学意义(P0.05),复发率明显低于对照组,差异有统计学意义(P0.05);观察组中人工喂养儿总有效率明显高于母乳喂养及混合喂养儿,差异有统计学意义(P0.05)。结论牛奶蛋白过敏是婴儿湿疹的常见病因,早期识别及早期回避可以明显减少婴儿湿疹的发生,改善不适症状,有利于儿童生长发育。
[Abstract]:Objective to investigate the relationship between milk protein allergy and infant eczema, and to study the effect of early identification and avoidance of milk protein allergy on infant eczema. Methods 241 infants with eczema were divided into two groups: observation group (n = 161) and control group (n = 80). The observation group was further divided into two groups: group A, pure breast-feeding group, mother avoiding milk and its products, group B were given amino acid formula milk or deep hydrolysate protein. In group C, the mother avoided milk products and added amino acid formula or deep hydrolysate formula. In the control group, normal formula or / and milk products could not be avoided by their mothers. The infants were followed up for 6 months after birth. Results at the age of 6 months, the total effective rate of eczema in the observation group was higher than that in the control group, the difference was statistically significant (P0.05), and the recurrence rate was significantly lower than that in the control group. The difference was statistically significant (P0.05); the total effective rate of artificial feeding in observation group was significantly higher than that of breast-feeding and mixed feeding (P0.05). Conclusion Milk protein allergy is a common cause of eczema in infants. Early identification and avoidance can significantly reduce the occurrence of eczema in infants, improve the symptoms of discomfort, and be beneficial to the growth and development of children.
【作者单位】：佛山市妇幼保健院儿童保健科;佛山市妇幼保健院皮肤科;
【基金】：佛山市医学类科技攻关项目(编号:2015AB0400)
【分类号】：R758.23

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