皮肤镜对常见色素减退性疾病的临床图像特征分析技术的建立

发布时间：2018-10-09 19:54

【摘要】：目的:建立皮肤镜对白癜风、白色糠疹、无色素痣、炎症后色素减少症、进行性斑状色素减少症、老年性白斑和贫血痣的临床图像特征分析技术。方法:分别观察1439例色素减退性疾病患者的皮损,用皮肤镜观察肉眼不可见的细微结构,如背景颜色、血管形态、边界情况、毛发及毛囊是否异常等。应用卡方检验和Fisher精确检验方法进行统计学分析。结果:瓷白色、花斑色和浅白色背景色度分别为白癜风稳定期、无色素痣和进行性斑状色素减少症的较特异性皮肤镜图像特征。灰白色糠状鳞屑是白色糠疹的特异性皮肤镜图像特征,可区别于其他疾病。进展期白癜风特征为乳白色背景,边界模糊,毛囊周围色素残留,周边点状、不规则状色素减退斑,斑片状色素残留。稳定期白癜风特征为瓷白色背景,边界清晰,毛囊周围色素残留,皮损周围色素加深。恢复期白癜风特征为边界清晰,毛囊周围色素残留,皮损周围色素加深,易见色素岛。白色糠疹特征为淡黄白色背景,表面细小或片状灰白色糠状鳞屑,边界模糊。无色素痣:花斑样背景,边界模糊,斑片状色素残留。炎症后色素减少症特征为黄白色背景,边界模糊。进行性斑片状色素减少症特征为浅白色背景,边界模糊。老年性白斑特征为乳白色背景,边界清晰。贫血痣特征为黄白色背景,边界模糊,摩擦后周边呈现网格状血管分布。结论:皮肤镜临床图像特征分析技术可作为诊断和鉴别诊断白癜风、白色糠疹、无色素痣、炎症后色素减少症、进行性斑状色素减少症、老年性白斑和贫血痣的一种辅助方法。
[Abstract]:Objective: to establish a technique for clinical image analysis of vitiligo, pityriasis albicans, non-pigmented nevus, postinflammatory pigmentopenia, progressive pigmentopenia, senile leukoplakia and anaemic nevus. Methods: the skin lesions of 1439 patients with hypochromatic diseases were observed respectively. The invisible fine structures such as background color, vascular morphology, boundary condition, hair and hair follicles were observed with dermatoscope. Chi-square test and Fisher accurate test were used for statistical analysis. Results: the background color of porcelain white, spot color and light white color were the specific features of dermoscope in stable stage of vitiligo, non-pigmented nevus and progressive pigmentopenia. Grayish-white bran scale is a specific dermatoscopic feature of pityriasis albicans and can be distinguished from other diseases. The progressive vitiligo is characterized by milky white background, blurred boundary, residual pigments around the hair follicles, spots around the hair follicles, irregular pigmentation spots and patches of pigments. Stable vitiligo is characterized by white porcelain background, clear boundary, residual pigments around the hair follicles and deep pigments around the lesions. Vitiligo in convalescence was characterized by clear boundary, residual pigments around the hair follicles, deep pigments around the lesions and easy to see pigment island. White pityriasis is characterized by yellowish-white background, small or flaky grayish white bran scale and blurred boundary. Non-pigmented nevus: spot like background, blurred border, patch pigment residue. Postinflammatory hypothyroidism is characterized by a yellowish-white background with blurred borders. Progressive macular pigmentopenia is characterized by a pale white background with a blurred boundary. The features of senile leukoplakia are milky white background and clear boundary. Anaemic nevus is characterized by yellowish-white background, blurred boundary and gridding distribution of blood vessels. Conclusion: the technique of clinical image characteristic analysis under dermatoscope can be used as an auxiliary method for the diagnosis and differential diagnosis of vitiligo, pityriasis albicans, non-pigmented nevus, postinflammatory pigmentopenia, progressive pigmentopenia, senile leukoplakia and anaemic nevus.
【作者单位】：安徽医科大学附属杭州临床学院;
【基金】：国家自然科学基金(81472887)资助项目
【分类号】：R758.4

【相似文献】