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放射性皮炎防治机制及措施研究

发布时间:2018-10-13 09:42
【摘要】:正放射治疗(以下简称"放疗")是治疗恶性肿瘤的主要治疗手段之一。60%的恶性肿瘤患者在治疗的不同阶段需要接受放疗。随着射线剂量的增加,射线不仅对肿瘤组织产生杀伤作用,还引起照射部位放射性皮炎,这是肿瘤放疗中最常见的并发症之一[1]。究其原因,除了射线本身的物理特性之外,同步化学药物治疗(化疗)、靶向药物和面罩固定等应用也是增加皮肤毒性的重要因素[2-3],如Ⅲ~Ⅳ期头颈部肿瘤患者行同步放疗和化疗(照射剂量≥66~70 Gy,化疗≥6
[Abstract]:Positive radiotherapy (hereinafter referred to as "radiotherapy") is one of the main treatment methods for malignant tumors. 60% of patients with malignant tumors need radiotherapy at different stages of treatment. With the increase of radiation dose, radiation not only can kill tumor tissue, but also cause radiation dermatitis. This is one of the most common complications in tumor radiotherapy [1]. The reason is that in addition to the physical properties of the ray itself, Simultaneous chemotherapeutic therapy (chemotherapy), targeted drugs and mask fixation are also important factors in increasing skin toxicity [2-3], such as concurrent radiotherapy and chemotherapy (radiation dose 鈮,

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