骶尾部皮肤纤毛囊肿1例并文献复习
发布时间：2018-12-10 17:16
【摘要】：目的探讨骶尾部皮肤纤毛囊肿(cutaneous ciliated cyst,CCC)的临床病理学特征、诊断、鉴别诊断及预后。方法回顾性分析1例骶尾部CCC的临床病理学、组织学发生及免疫表型特征并复习相关文献。结果患者女童,11岁,发现骶尾部臀裂处赘生物、盆腔MRI尾骨后软组织内边界清楚的囊肿。镜下见真皮层及皮下组织内囊肿形成,与表皮不相连,囊腔内上皮细胞呈乳头状生长,可见鳞状上皮化生,衬覆上皮类似输卵管上皮,由假复层纤毛柱状上皮及分泌细胞组成,未见胞质内分泌物及顶质分泌,未见肌上皮细胞。免疫表型:上皮细胞表达ER、PAX-8,不表达GCDFP-15、TTF-1。结论骶尾部CCC属罕见的良性囊肿,该例起源于异位的Müllerian上皮,确诊主要依靠病理学形态及免疫表型,手术切除后不复发。
[Abstract]:Objective to investigate the clinicopathological features, diagnosis, differential diagnosis and prognosis of sacrococcygeal skin ciliated cysts (cutaneous ciliated cyst,CCC). Methods A case of sacrococcygeal CCC was retrospectively analyzed in terms of clinicopathology, histopathology and immunophenotypic features. Results the 11-year-old girl found a neoplasm at the sacrococcygeal fissure and a cyst with clear internal boundaries in the soft tissue behind the pelvic MRI. Under microscope, the cysts in the dermis and subcutaneous tissue formed, which were not connected with the epidermis. The epithelial cells in the capsule were papillary. The squamous metaplasia was seen, and the lining epithelium was similar to the tubal epithelium, which was composed of the pseudostratified ciliated columnar epithelium and secretory cells. There was no cytoplasmic secretion and acroplasm secretion, and no myoepithelial cells. Immunophenotype: epithelial cells express ER,PAX-8, and do not express GCDFP-15,TTF-1. Conclusion sacrococcygeal CCC is a rare benign cyst, which originated from the ectopic M 眉 llerian epithelium. The diagnosis of sacrococcygeal CCC mainly depends on pathological morphology and immunophenotype, and does not recur after resection.
【作者单位】： 南京中医药大学附属医院病理科;南京中医药大学附属医院放射科;
【分类号】：R751
本文编号：2370935
[Abstract]:Objective to investigate the clinicopathological features, diagnosis, differential diagnosis and prognosis of sacrococcygeal skin ciliated cysts (cutaneous ciliated cyst,CCC). Methods A case of sacrococcygeal CCC was retrospectively analyzed in terms of clinicopathology, histopathology and immunophenotypic features. Results the 11-year-old girl found a neoplasm at the sacrococcygeal fissure and a cyst with clear internal boundaries in the soft tissue behind the pelvic MRI. Under microscope, the cysts in the dermis and subcutaneous tissue formed, which were not connected with the epidermis. The epithelial cells in the capsule were papillary. The squamous metaplasia was seen, and the lining epithelium was similar to the tubal epithelium, which was composed of the pseudostratified ciliated columnar epithelium and secretory cells. There was no cytoplasmic secretion and acroplasm secretion, and no myoepithelial cells. Immunophenotype: epithelial cells express ER,PAX-8, and do not express GCDFP-15,TTF-1. Conclusion sacrococcygeal CCC is a rare benign cyst, which originated from the ectopic M 眉 llerian epithelium. The diagnosis of sacrococcygeal CCC mainly depends on pathological morphology and immunophenotype, and does not recur after resection.
【作者单位】： 南京中医药大学附属医院病理科;南京中医药大学附属医院放射科;
【分类号】：R751
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1 万颖;张剑;罗粤;杨湛幸;曾俊锋;张岚;李文龙;张君忠;;骶尾部压疮合并变态反应性皮肤病误诊1例报道[J];中国民康医学;2012年21期
，本文编号：2370935
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