不同过敏原检测方法在结节性痒疹患者中的应用

发布时间：2018-12-21 13:26

【摘要】：目的为结节性痒疹(PN)患者过敏原检测方法的选择提供临床依据,并进一步研究PN过敏原的分布特征。方法 PN患者262例分4组进行点刺试验(54例)、斑贴试验(50例)、血清IgE过敏原检测(56例)和血清IgG过敏原检测(102例),系统分析PN患者各项过敏原阳性率和分布差异。结果与对照组比较,54例PN患者点刺试验中法桐、艾蒿、杨树、粉尘螨、屋尘螨、鳕鱼、花生和番茄的阳性率增高(P0.05);50例PN患者斑贴试验中硫酸镍、芳香混合物、黑橡胶混合物和卡巴混合物阳性率增高(P0.05);56例PN患者血清IgE试验中屋尘、凬草、猫毛/狗毛、蟑螂、青霉/孢霉和羊肉阳性率增高(P0.05);102例PN患者血清IgG试验中蟹、虾、牛肉、鳕鱼阳性率增高(P0.05)。结论点刺试验、血清IgE检测在PN患者中的应用非常重要,血清IgG检测对PN患者饮食结构的调整也有一定意义,而斑贴试验在PN中的应用意义还需要进一步探讨。
[Abstract]:Objective to provide clinical basis for the selection of allergen detection methods in patients with prurigo nodule (PN) and to further study the distribution of PN allergens. Methods 262 patients with PN were divided into 4 groups: prick test (54 cases), patch test (50 cases), serum IgE allergen test (56 cases) and serum IgG allergen test (102 cases). Results compared with the control group, the positive rates of Falton, Artemisia, Poplar, Dermatophagoides farinae, Cod, Peanut and Tomato increased in 54 patients with PN (P0.05). The positive rates of nickel sulfate, aromatic mixture, black rubber mixture and carbapa mixture in 50 PN patients were increased (P0.05). The positive rates of house dust, grass, cat hair / dog hair, cockroach, penicillium / spore and mutton were increased in serum IgE test of 56 patients with PN (P0.05), and the positive rates of crab, shrimp, beef and cod in serum IgG test of 102 patients with PN were increased (P0.05). Conclusion the application of prick test and serum IgE in patients with PN is very important. The detection of serum IgG also has some significance for the adjustment of dietary structure of PN patients, and the application significance of plaque test in PN needs to be further explored.
【作者单位】：西安交通大学医学部;宝鸡市中心医院皮肤科;
【基金】：陕西省宝鸡市卫生局科研立项课题(No.2012-15)~~
【分类号】：R758.6

【相似文献】