深圳市2523例妊娠梅毒患者性伴的梅毒感染情况分析

发布时间：2019-02-17 18:51

【摘要】：目的了解妊娠梅毒患者性伴的梅毒感染情况及相关影响因素。方法对确诊的妊娠梅毒患者进行随访和性伴追踪,对就诊的性伴采用甲苯胺红不加热血清试验(TRUST)和梅毒螺旋体明胶颗粒凝集试验(TPPA)检测。通过结构化问卷收集性伴相关信息。结果 2008-2011年间,深圳市共确诊妊娠梅毒患者3551例,其中2523例患者的性伴自愿到产前门诊就诊并进行梅毒血清学检测,妊娠梅毒患者性伴的检测率为71.05%。接受调查的性伴中,577例TRUST和TPPA检测均阳性(22.87%),134例仅TPPA阳性(5.31%),妊娠梅毒患者性伴的梅毒感染率为28.18%(711/2523)。多因素Logistic回归模型结果显示,年龄、婚姻状态、文化水平、职业和多性伴与性伴感染梅毒有关。多性伴者感染梅毒的风险是单一性伴者的1.55倍[比值比(OR)=1.55,95%可信区间(CI)=1.26~1.90]。结论妊娠梅毒患者性伴的梅毒感染率较高,多性伴行为是性伴感染梅毒的重要危险因素。
[Abstract]:Objective to investigate syphilis infection and related factors in pregnant syphilis patients. Methods the patients with syphilis during pregnancy were followed up and followed up. The sex partners were detected by toluidine red unheated serum test (TRUST) and syphilis gelatin particle agglutination test (TPPA). The information about sex partners was collected by structured questionnaire. Results from 2008 to 2011, 3551 pregnant syphilis patients were diagnosed in Shenzhen. Among them, 2523 of them volunteered to visit antepartum outpatient clinic and tested syphilis serology. The detection rate of sexual partners in pregnant syphilis patients was 71.05%. Among the sexual partners surveyed, 577 (22.87%) were positive for TRUST and TPPA, 134 (5.31%) for TPPA, and 28.18% (711 / 2523) for syphilis in pregnant syphilis patients. The results of multivariate Logistic regression model showed that age, marital status, educational level, occupation and multiple partners were associated with syphilis. The risk of syphilis infection in polysexual partners was 1.55 times higher than that in single partners [(OR) = 1.55V 95% confidence interval (CI) = 1.261.90)]. Conclusion the infection rate of syphilis was higher in pregnant syphilis patients, and polysexual behavior was an important risk factor for syphilis infection.
【作者单位】：深圳市慢性病防治中心;
【基金】：广东省医学科研基金项目(B2013357)~~
【分类号】：R759.15

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