长链非编码RNA在皮肤病中的研究进展
发布时间：2019-08-12 18:09
【摘要】：长链非编码RNA(Lnc RNA)是一类长于200个核苷酸的不编码蛋白质的转录物。它一度被认为是基因组转录的"噪音",不具有生物学功能。近年来研究表明,Lnc RNA有着复杂的生物学功能,与皮肤病等人类疾病的发生及发展有着密切关系,其异常表达还与多种人类重大疾病的发生密切相关。该文对Lnc RNA的分类、基本特征、作用机制、功能以及其在皮肤病中的研究进展作一综述。
[Abstract]:Long chain non-coding RNA (Lnc RNA) is a class of transcripts of unencoded proteins longer than 200nucleotides. It was once thought to be the "noise" of genome transcription and did not have biological functions. In recent years, studies have shown that, Lnc RNA has complex biological functions, which is closely related to the occurrence and development of human diseases such as skin diseases, and its abnormal expression is also closely related to the occurrence of many major human diseases. In this paper, the classification, basic characteristics, mechanism of action, function and research progress of Lnc RNA in dermatosis are reviewed.
【作者单位】： 西南医科大学临床医学院;重庆市第一人民医院皮肤科;
【基金】：重庆市科学技术委员会基础科学与前沿技术研究专项基金(cstc2016jcyjA0179)资助项目
【分类号】：R751
本文编号：2525876
[Abstract]:Long chain non-coding RNA (Lnc RNA) is a class of transcripts of unencoded proteins longer than 200nucleotides. It was once thought to be the "noise" of genome transcription and did not have biological functions. In recent years, studies have shown that, Lnc RNA has complex biological functions, which is closely related to the occurrence and development of human diseases such as skin diseases, and its abnormal expression is also closely related to the occurrence of many major human diseases. In this paper, the classification, basic characteristics, mechanism of action, function and research progress of Lnc RNA in dermatosis are reviewed.
【作者单位】： 西南医科大学临床医学院;重庆市第一人民医院皮肤科;
【基金】：重庆市科学技术委员会基础科学与前沿技术研究专项基金(cstc2016jcyjA0179)资助项目
【分类号】：R751
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