中国汉族特应性皮炎4757例患者过敏史相关性分析
发布时间:2019-08-12 17:43
【摘要】:目的探讨中国汉族特应性皮炎(AD)患者同时患有过敏性鼻炎(allergic rhinitis,AR)、哮喘(asthma,AS)等疾病时对AD表型的影响。方法利用2001年11月-2010年5月收集的4 757例AD患者资料,采用SPSS20.0软件进行卡方检验,分析不同过敏史对AD表型的影响。结果 1AD同时患有AR与南方地区(P=1.51×10~(-18))正相关,与伴发耳廓下裂隙(P=1.75×10~(-7))负相关,与其他表型无关;2AD同时患有AS与南方地区(P=4.39×10~(-20))、掌纹症(P=5.06×10~(-9))、眶周黑晕(P=3.10×10~(-7))正相关,与伴发干皮症(P=2.13×10~(-6))、早年发病(P=1.35×10~(-3))、耳廓下裂隙(P=1.35×10~(-4))负相关,与其他表型无关;3AD同时患有AR+AS与南方地区(P=2.76×10~(-13))、伴发掌纹症(P=1.70×10~(-5))、眶周黑晕(P=2.42×10~(-5))正相关,与其他表型无关;4AD伴过敏家族史与毛周角化症(P=1.46×10~(-3))、耳廓下裂隙(P=3.34×10~(-5))正相关,与南方地区(P=4.63×10~(-32))负相关,与其他表型无关。结论 AD伴发不同过敏史与不同地域有关,同时影响伴发症状的发生。
[Abstract]:Objective to investigate the effect of allergic rhinitis (allergic rhinitis,AR) and asthma (asthma,AS) on AD phenotype in Chinese Han patients with atopic dermatitis (AD). Methods the data of 4757 patients with AD collected from November 2001 to May 2010 were analyzed by chi-square test with SPSS20.0 software. The effects of different allergic history on AD phenotype were analyzed. Results AR was positively correlated with AR in southern China (P 鈮,
本文编号:2525865
[Abstract]:Objective to investigate the effect of allergic rhinitis (allergic rhinitis,AR) and asthma (asthma,AS) on AD phenotype in Chinese Han patients with atopic dermatitis (AD). Methods the data of 4757 patients with AD collected from November 2001 to May 2010 were analyzed by chi-square test with SPSS20.0 software. The effects of different allergic history on AD phenotype were analyzed. Results AR was positively correlated with AR in southern China (P 鈮,
本文编号:2525865
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