急性脑梗死患者同型半胱氨酸与颈动脉斑块的相关分析

发布时间：2017-12-27 23:25

本文关键词：急性脑梗死患者同型半胱氨酸与颈动脉斑块的相关分析　出处：《临床医药文献电子杂志》2016年48期 　论文类型：期刊论文

【摘要】：目的分析急性脑梗死患者同型半胱氨酸与颈动脉斑块的相关性。方法选取2015年6月~2016年6月我院急性脑梗死患者100例为研究对象,将有斑块的患者分为研究组,无斑块患者分为常规组,各50例。使用彩色多普勒超声检测患者颈动脉粥样硬化斑块的有无,以及斑块厚度、膜厚度。发病3d内测量血清HCY水平。结果研究组HCY中位数为12.5μmol/L,常规组HCY中位数为15.6μmol/L,Spearman检验表明颈动脉斑块最大厚度与HCY关系为正相关,差异有统计学意义(r=0.235,P0.05)。回顾性分析Logistic表明,患者年龄、高血压病史、男性性别是影响斑块形成的主要原因,而HCY与斑块形成无关系,HCY与颈动脉斑块最大厚度关系为正相关。结论研究组患者HCY明显高于常规组,HCY与颈脉动斑块最大厚度关系,呈正相关。
[Abstract]:Objective to analyze the correlation between homocysteine (homocysteine) and carotid plaque in patients with acute cerebral infarction. Methods a total of 100 patients with acute cerebral infarction in our hospital from June 2015 to June ~2016 were selected as the research subjects. Patients with plaques were divided into study group, and no plaques were divided into routine group and 50 case group. Color Doppler ultrasound was used to detect the carotid atherosclerotic plaque, and the thickness of plaque and the thickness of the membrane. Serum levels of HCY were measured in 3D. Results the median of HCY in the study group was 12.5 mol/L, and the median HCY in the conventional group was 15.6 mol/L. The Spearman test showed that the relationship between the maximum thickness of carotid plaques and HCY was positively correlated, and the difference was statistically significant (r=0.235, P0.05). A retrospective analysis of Logistic showed that age, history of hypertension and male sex were the main causes of plaque formation. HCY was not correlated with plaque formation. HCY was positively correlated with the maximum thickness of carotid plaques. Conclusion the HCY of the patients in the study group was significantly higher than that of the conventional group, and the relationship between HCY and the maximum thickness of the cervical pulsating plaque was positively correlated.
【作者单位】：南京鼓楼医院集团宿迁市人民医院;
【分类号】：R743.33
【正文快照】： 颈动脉斑块是影响缺血性卒中最主要的一个危险原因,有关研究表明,颈动脉斑块患者的同型半胱氨酸明显高于其他人群[1]。但是针对急性脑梗死患者而言,HCY与颈脉动斑块最大厚度之间的关系,尚未完全明确[2]。本文就此探讨急性脑梗死患者同型半胱氨酸与颈动脉斑块的相关性。现报道

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