甘露醇联合甘油果糖治疗脑出血的效果观察

发布时间：2018-01-16 01:08

本文关键词：甘露醇联合甘油果糖治疗脑出血的效果观察　出处：《中国实用神经疾病杂志》2016年23期 　论文类型：期刊论文

更多相关文章： 脑出血 甘露醇 甘油果糖 安全性

【摘要】：目的观察甘露醇联合甘油果糖治疗脑出血的效果,分析其安全性。方法 2014-02—2015-05我院90例脑出血患者随机分为对照组(n=45)和观察组(n=45),对照组给予甘油果糖治疗,观察组在对照组治疗基础上加用甘露醇,记录并分析治疗后2组血肿体积、神经功能评分、治疗状况及并发症状况。结果治疗后观察组血肿体积、神经功能评分分别为(10.1±1.7)mL、(10.6±1.9)分,均低于对照组的(17.9±2.1)mL、(16.2±2.3)分,差异均有统计学意义(P0.05)。观察组总有效率为93.33%,高于对照组的75.56%,差异均有统计学意义(P0.05)。观察组肾功能损害及电解质紊乱发生率分别为6.7%、6.7%,对照组分别为8.9%、4.4%,差异无统计学意义(P0.05)。结论甘露醇联合甘油果糖用于脑出血的治疗,可显著改善患者血肿和神经功能缺损状况,且未见明显不良反应。
[Abstract]:Objective to observe the effect of mannitol combined with fructose glycerol on intracerebral hemorrhage. Methods 90 patients with intracerebral hemorrhage in our hospital were randomly divided into control group (n = 45) and observation group (n = 45). The control group was treated with glycerol fructose and the observation group was treated with mannitol on the basis of the control group. The hematoma volume and neurological function score were recorded and analyzed after treatment. Results after treatment, the hematoma volume and neurological function score of the observation group were 10.1 卤1.7 mL / L and 10.6 卤1.9 respectively. The difference was statistically significant (P 0.05). The total effective rate of the observation group was 93.33%. Compared with the control group, the difference was statistically significant (P 0.05). The incidence of renal dysfunction and electrolyte disturbance in the observation group was 6.7%. There was no significant difference in the control group (P 0.05). Conclusion mannitol combined with glycerol fructose is used in the treatment of intracerebral hemorrhage. It can significantly improve the hematoma and neurological deficit, and no obvious adverse reactions.
【作者单位】：陕西省第四人民医院神经内科;
【分类号】：R743.34
【正文快照】： 脑出血是常发于老年人群的一组脑血管疾病,具有发病突然、高致残性及高致死率等特点,且一旦病发病往往病情较重,甚至会威胁患者生命[1]。文献[2]报道,我国脑出血的发病率为0.3%左右,老年人发病率高于青年,近几年脑出血发病年龄逐渐呈现年轻化趋势。脑出血后遗症较多,文献[3]报

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