Solitaire AB与Enterprise支架辅助栓塞颅内宽颈动脉瘤患者的疗效对比

发布时间：2018-01-21 13:57

本文关键词： 颅内动脉瘤 Enterprise支架 Solitaire AB支架支架辅助栓塞　出处：《中国脑血管病杂志》2016年10期 　论文类型：期刊论文

【摘要】：目的比较Solitaire AB与Enterprise支架对血管内辅助栓塞颅内宽颈动脉瘤的效果。方法回顾性分析广东省人民医院2012年1月至2014年12月采用Solitaire AB或Enterprise支架治疗的218例颅内宽颈动脉瘤患者的临床资料。其中使用Solitaire AB支架治疗(Solitaire AB组)70例,Enterprise治疗(Enterprise组)148例。随访时间为术后2个月至2年,以术后Raymond分级和改良Rankin量表(mRS)评分对两种支架的疗效进行比较。结果术前两组患者Hunt-Hess分级(Z=1.550,P=0.121)、Fisher分级(Z=1.537,P=0.124)、动脉瘤大小(Z=0.192,P=0.848)和部位(χ~2=0.337,P=0.736)差异均无统计学意义。术后两组患者即刻Raymond分级(Z=0.682,P=0.495)、随访Raymond分级(Z=0.206,P=0.837)和mRS评分(P=0.662)比较,差异均无统计学意义。进一步行多因素Logistic回归分析,显示支架种类不是影响预后的因素[随访Raymond分级(OR=0.029,95%CI:0.126~0.199,P=0.661)和术后mRS评分(OR=2.000,95%CI:0.204~19.603,P=0.552]。结论 Solitaire AB和Enterprise支架辅助栓塞颅内宽颈动脉瘤效果均良好。
[Abstract]:Objective to compare Solitaire. AB and Enterprise stents were used for endovascular embolization of intracranial wide-necked aneurysms. Methods Soli was used in Guangdong Provincial people's Hospital from January 2012 to December 2014. Taire. Clinical data of 218 patients with wide carotid aneurysm treated with AB or Enterprise stents. 70 cases of Solitaire AB group. 148 cases were treated with Enterprise. The follow-up time was 2 months to 2 years after operation. The efficacy of the two stents was compared with the Raymond grade and the modified Rankin scale mRS. Results the Hunt-Hess scores of the two groups were compared before operation (P < 0.05). ZN 1.550. The size of the aneurysm was 0.192 and the size of the aneurysm was 0.192. There was no significant difference in P0. 848) and the site (蠂 2: 0. 337, P0. 736). There was no significant difference between the two groups in immediate Raymond grade (P 0. 682). The results were compared with that of mRS score (P < 0. 662) and Raymond grade (P = 0. 206) and mRS score (P = 0. 662). Further multivariate Logistic regression analysis showed that the type of stent was not a prognostic factor. [The Raymond grade was 0.029 ~ 95% (CI: 0.126 卤0.199P0.661) and the postoperative mRS score was 2.000 (P < 0.05). I am 95 CI: 0.204 and 19.603. Conclusion Solitaire AB and Enterprise stents are effective in embolization of intracranial wide carotid aneurysms.
【作者单位】：广东省医学科学院广东省人民医院神经外科;
【基金】：广东省科技计划(2016A020212008)
【分类号】：R743
【正文快照】： 颅内宽颈动脉瘤的血管内治疗策略主要包括支架结合弹簧圈栓塞和球囊辅助技术[1-3]。支架使用的目的之一是重塑瘤颈,阻挡动脉瘤内弹簧圈疝入载瘤动脉[4-5]。目前,国内用于颅内动脉瘤的支架主要有Neuroform、Leo、Enterprise和Solitaire AB。Enterprise支架直径只有一种(4.5 mm)

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