H型高血压与缺血性脑卒中的相关性研究

发布时间：2018-01-26 12:38

本文关键词： 高血压 H型缺血性脑卒中 TOAST分型　出处：《现代实用医学》2016年12期 　论文类型：期刊论文

【摘要】：目的探讨H型高血压与缺血性脑卒中的相关性。方法采集368例急性缺血性脑卒中患者的病史,检测同型半胱氨酸、血脂、血糖及尿酸等指标,比较缺血性脑卒中合并H型高血压患者的临床特征及其与TOAST分型的关系,并与198例体检者(对照组)进行比较。结果缺血性脑卒中组高血压病患病率、吸烟比例、血Hcy高于对照组,HDL-C低于对照组(均P0.05);合并H型高血压组在男性、2型糖尿病及吸烟者比例,年龄及血Hcy、尿酸高于其他缺血性脑卒中患者(均P0.05);在TOAST亚型中的分布情况与其他组类似。结论高血压病、吸烟、血HDL-C水平降低、Hcy水平升高是缺血性脑卒中的独立危险因素。缺血性脑卒中合并H型高血压者男性为主,常合并年龄大、2型糖尿病、吸烟、血尿酸水平升高等危险因素。H型高血压对TOAST各亚型的影响没有特异性。
[Abstract]:Objective to investigate the correlation between H type hypertension and ischemic stroke. Methods 368 patients with acute ischemic stroke were collected and the indexes of homocysteine, blood lipid, blood glucose and uric acid were detected. To compare the clinical characteristics of ischemic stroke patients with H type hypertension and its relationship with TOAST classification. Results the prevalence of hypertension, smoking rate and serum Hcy in ischemic stroke group were higher than those in control group (all P 0.05). The proportion of type 2 diabetes mellitus and smokers, age, blood Hcyand uric acid in patients with H type hypertension were higher than those in other ischemic stroke patients (all P 0.05). The distribution in TOAST subtype was similar to that in other groups. Conclusion Hypertension, smoking, and blood HDL-C level are decreased. Elevated Hcy level is an independent risk factor for ischemic stroke. Men with ischemic stroke associated with type H hypertension are mainly males, often associated with older type 2 diabetes mellitus and smoking. The effect of H-type hypertension on the subtypes of TOAST was not specific.
【作者单位】：温州市中心医院;
【基金】：浙江省温州市科技计划项目(Y20140524)
【分类号】：R544.1;R743.3
【正文快照】： 脑卒中具有高发病率、高死亡率、高致残率及高复发率的特点,对各种危险因素如高血压、糖尿病、高脂血症及高同型半胱氨酸(Hcy)血症等的有效干预,是防止和延缓脑卒中、冠心病等疾病发生、发展的主要措施之一。中国人群,尤其是高血压患者中的一个重要特点就是血浆Hcy水平高,我国

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