影像学特征与脑膜瘤术后复发的相关性研究

发布时间：2018-01-28 23:46

本文关键词： 脑膜瘤影像学特征肿瘤复发　出处：《桂林医学院》2014年硕士论文　论文类型：学位论文

【摘要】：目的：分析非复发组和复发组脑膜瘤患者的年龄、肿瘤最大直径、肿瘤的发生部位、肿瘤的形状、肿瘤周围的水肿情况、肿瘤的影像学下密度、强化情况和钙化情况与脑膜瘤术后复发之间的相关性。应用这些手段综合分析即可在术前评价患者的复发风险,从而制定出完善的诊疗措施,并采取相应的预防和治疗手段,改善患者的预后。方法：收集2005-2013年广西壮族自治区南溪山医院神经外科经手术切除并病理证实的脑膜瘤病例共119例。我们将这些病例按照非复发和复发分为两组。非复发组选取病人95例,复发组选取病人24例。比较非复发组与复发组之间的患者的年龄、肿瘤最大直径、肿瘤的发生部位、肿瘤的形状、肿瘤周围的水肿情况、肿瘤的影像学下密度、强化情况和钙化情况等影像学特征(CT或MRI),分析其有无统计学差异。结果：复发组肿瘤位于大脑凸面、矢状窦旁、大脑镰旁及颅底分别占50.0%(12/24)、8.3%(2/24)、16.7%(4/24)、25.0%(6/24；非复发组分别为44.2%(42/95)、6.3%(6/95)、16.9%(16/95)、32.6%(31/95),两组比较差异有统计学意义(P0.05)；复发组肿瘤为圆形、分叶形和蘑菇形脑膜瘤者分别占54.17%(13/24)、29.16%(7/24)、16.67%(4/24),非复发组则为68.4%(65/95)、22.1%(21／95)、9.5%(9/95),两组比较差异有统计学意义(P0.05)；复发组瘤内有钙化25%(6/24),高于非复发组的3.2%(3/95)(P0.05)；复发组发生骨质改变37.50%(9/24),高于非复发组的9.5%(9/95)(P0.05)；两组肿瘤大小、有无硬脑膜尾征、有无均一强化以及瘤周水肿程度比较,差异无统计学意义(P0.05)。结论：1、脑膜瘤的发生和进展和复发是一个连续的、全身的过程,受多种因素的影响。 2、影像学检查可以在一定程度上帮助诊断复发性脑膜瘤。
[Abstract]:Objective: to analyze the age, tumor diameter, tumor location, tumor shape, edema around the tumor, and imaging density of meningiomas in non-recurrent and relapsed groups. The correlation between enhancement and calcification and postoperative recurrence of meningioma. Comprehensive analysis of these methods can be used to evaluate the risk of recurrence of patients before the operation, so as to formulate a sound diagnosis and treatment measures. And adopt the corresponding prevention and treatment to improve the prognosis of patients. Methods:. 119 cases of meningioma confirmed by surgery and pathology in Nanxi Mountain Hospital of Guangxi Zhuang Autonomous region from 2005 to 2013 were collected. These cases were divided into two groups according to their non-recurrence and recurrence. 95 patients in non-recurrence group were selected. 24 patients were selected in the recurrent group. The age, the maximum diameter of the tumor, the location of the tumor, the shape of the tumor and the edema around the tumor were compared between the non-recurrence group and the recurrent group. The imaging features of tumor were CT or MRI, such as density, enhancement and calcification. Results: the recurrent tumors were located on the convex surface of the brain, next to the sagittal sinus, and the cerebral falx and skull base accounted for 50.0%, respectively. 25.0 / 24; In the non-recurrence group, 44.2% / 42 / 95 / 6.3a, respectively, about 16 / 95 / 16.9 and 32.632 / 95 respectively). The difference between the two groups was statistically significant (P 0.05). The recurrent tumors were round, lobular and mushroom meningiomas, accounting for 13 / 24 / 29. 16 / 7 / 24 and 16.67 / 4 / 24, respectively. In the non-recurrence group, the ratio was 68.4% (65 / 95) and 22.1b / 21 / 95 / 95 / 9 / 95 / 95. The difference between the two groups was statistically significant (P 0.05). The calcification of 25 / 24% of the tumor in the recurrent group was higher than that in the non-recurrence group (3.2 / 95 / P0.05). The incidence of bone change in recurrent group was 37.50 / 9 / 24, which was higher than that in non-recurrence group (9.5% 95% P 0.05). There was no significant difference in tumor size, dural caudal sign, homogeneous enhancement and degree of peritumoral edema between the two groups (P 0.05). ConclusionThe occurrence, progression and recurrence of meningioma are a continuous, systemic process, which is influenced by many factors. 2, imaging examination can help to diagnose recurrent meningioma to some extent.
【学位授予单位】：桂林医学院
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R739.45

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