脑卒中后癫痫的临床特征及其预后分析

发布时间：2018-02-04 04:02

本文关键词： 脑卒中癫痫脑梗死脑出血脑卒中后癫痫　出处：《吉林医学》2013年04期 　论文类型：期刊论文

【摘要】：目的:探讨脑卒中后癫痫的发病机制、临床特点及预后。方法:采用流行病学分析方法,对本院脑卒中后癫痫33例患者临床资料进行回顾性分析。结果:脑卒中后癫痫发生率3.32%,其中早发性癫痫发生率0.2%,迟发性癫痫发生率3.30%。皮层病灶继发癫痫66.67%,皮层下病灶继发癫痫33.33%,两者比较,差异有统计学意义(P0.05)。部分性发作8例(24.24%)。全身强直阵挛性发作22例和癫痫持续状态3例,占75.76%。出血性卒中继发癫痫占所有脑出血患者的9.62%,缺血性卒中继发癫痫占所有脑梗死患者的2.30%,两者比较差异有统计学意义(P0.05)。2例早发性癫痫者,患者服药期间无再发作。31例迟发性癫痫患者,有3例偶再发作,1例患者联合应用两种抗癫痫药治疗不能有效控制发作。早发性癫痫与迟发性癫痫比较,疗效均较好,两者比较差异无统计学意义(P0.05)。结论:脑卒中后癫痫以迟发性癫痫多见,皮层病灶较皮层下病灶易发生癫痫,以全面性发作为多见。出血性卒中易继发癫痫。脑卒中后癫痫疗效好。
[Abstract]:Objective: to investigate the pathogenesis, clinical characteristics and prognosis of epilepsy after stroke. The clinical data of 33 patients with post-stroke epilepsy in our hospital were retrospectively analyzed. Results: the incidence of post-stroke epilepsy was 3.32, of which the incidence of early epilepsy was 0.2%. The incidence of delayed epilepsy was 3.30%. The secondary epilepsy was 66.67 in cortical focus and 33.33 in subcortical lesion. The difference was statistically significant (P < 0.05), partial seizure (n = 8), generalized tonic-clonic seizure (n = 22) and status epilepticus (n = 3). Secondary epilepsy accounted for 9.62% of all cerebral hemorrhage patients, and ischemic stroke secondary epilepsy accounted for 2.30% of all cerebral infarction patients. There was a significant difference between the two groups (P 0.05%). There were no recurrent seizures during the treatment period. There were 3 cases of occasional recurrent seizures in 31 patients with delayed epilepsy. One patient who was treated with two kinds of antiepileptic drugs could not control the seizure effectively. The curative effect of early epilepsy was better than that of delayed epilepsy. There was no significant difference between the two groups (P0.050.Conclusion: delayed epilepsy is more common in post-stroke epilepsy, and the cortical focus is more prone to epilepsy than subcortical focus. Haemorrhagic stroke is prone to secondary epilepsy.
【作者单位】：江苏省南京同仁医院神经内科;
【分类号】：R742.1
【正文快照】： 脑卒中是危害人类健康的常见病、多发病,也是成人癫痫最常见的病因之一,卒中后癫痫不仅影响卒中患者的神经功能恢复,而且使脑卒中的致残率和致死率明显增加,给社会,家庭和个人带来沉重的负担。对脑卒中后癫痫的发病概况和发病规律及其预后的探讨,有助于更好的预防和治疗脑卒

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