降钙素原及T细胞亚群对急性脑梗死后感染的诊断价值研究

发布时间：2018-02-06 03:40

本文关键词： 降钙素 T淋巴细胞亚群急性病脑梗死抗原 CD 抗原 CD 感染　出处：《重庆医学》2017年26期 　论文类型：期刊论文

【摘要】：目的研究降钙素原及T细胞亚群对急性脑梗死后感染的诊断价值。方法选取2015年2月至2016年1月在该院进行诊治的急性脑梗死患者122例,根据患者脑梗死后是否发生感染分为感染组(60例)和未感染组(62例)。分别对比两组入院时收缩压、舒张压、体温、美国国立卫生研究所卒中量表(NIHSS)评分,以及脑梗死发生部位,降钙素原、CD4、CD8水平,并进行Logistic回归分析。结果感染组NIHSS评分为(14.9±5.7)分,明显高于未感染组的(10.6±3.8)分(P0.01)。感染组脑桥梗死人数占比为35.48%,明显高于未感染组的17.74%(P0.05)。感染组降钙素原明显高于未感染组,而CD4、CD8水平则明显低于未感染组(P0.05)。经多因素Logistic回归分析,影响急性脑梗死后感染的危险因素包括脑桥梗死、NIHSS评分、降钙素原、CD4及CD8水平。结论临床工作中通过对急性脑梗死患者的降钙素原与T细胞压群进行检查,有利于预测感染的发生。
[Abstract]:Objective to study the procalcitonin and T cell subsets in diagnosis of infection after acute cerebral infarction. Methods 122 patients with acute cerebral infarction from February 2015 to January 2016 were treated in the hospital patients, according to whether the occurrence of infection in patients with cerebral infarction were divided into infection group (60 cases) and non infection group (62 cases) were compared to two. Group admission systolic blood pressure, diastolic blood pressure, body temperature, the American National Institutes of Health Stroke Scale (NIHSS) score and cerebral infarction area, procalcitonin, CD4, CD8, and Logistic regression analysis. Results the infection group NIHSS score was (14.9 + 5.7), significantly higher than that in non infection group (10.6 + 3.8)% (P0.01). The infection group number of pontine infarction accounted for 35.48%, significantly higher than that in non infection group 17.74% (P0.05). The infection group of procalcitonin was higher than that of uninfected group, and CD4, CD8 levels were significantly lower than non infected group (P0.05). Multivariate Logistic back Regression analysis showed that the risk factors of infection after acute cerebral infarction included pons infarction, NIHSS score, procalcitonin, CD4 and CD8 level. Conclusion the detection of procalcitonin and T cell population in patients with acute cerebral infarction is helpful for predicting the occurrence of infection.

【作者单位】：海南省海口市人民医院神经内科;海南省海口市人民医院肿瘤化疗科;
【分类号】：R743.33

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