年龄因素对闪光视觉诱发电位无创颅内压监测技术检测颅内压准确性的影响

发布时间：2018-02-10 15:28

本文关键词： 闪光视觉诱发电位无创颅内压监测技术年龄颅内压腰椎穿刺　出处：《中国老年学杂志》2017年17期 　论文类型：期刊论文

【摘要】：目的探讨闪光视觉诱发电位无创颅内压监测技术(FVEP-NIICPM)与腰椎穿刺技术检测的差异及年龄因素对应用FVEP-NIICPM技术检测颅内压的影响。方法选取航天中心医院神经科诊断过程中根据病情需要行腰椎穿刺术并签署知情同意书的患者150例,将年龄分3组:18~40岁为青年组(47例);41~65岁为中年组(56例);66~80岁为老年组(47例)。应用FVEP-NIICPM技术检测受试对象的颅内压,之后立即行腰椎穿刺并记录脑脊液初压。结果 FVEP-NIICPM检测值与腰穿颅内压测量值有显著差异(Z=-3.793,P=0.001);相关性分析显示,应用FVEP-NIICPM得到的检测值与腰椎穿刺测得的颅内压值存在正相关(r=0.867,P=0.001)。不同年龄、性别、疾病诊断种类患者应用FVEP-NIICPM技术与腰椎穿刺技术测量的颅内压差值均无显著差异(P0.05)。结论应用FVEP-NIICPM技术与腰椎穿刺技术测得的颅内压值不同,有统计学差异(P0.05),但二者所测数值具有显著正相关性,且两种方法所测得颅内压平均值绝对差值仅为5.5 mm H_2O,基本反映颅内压的实际情况不影响对临床上的指导意义;年龄因素对FVEP-NIICPM技术测量颅内压无明显影响。
[Abstract]:Objective to explore the difference between FVEP-NIICPMM and lumbar puncture technique in monitoring intracranial pressure with flash visual evoked potential (FVEP-NIICPMP) and the influence of age factors on intracranial pressure by FVEP-NIICPM technique. Methods the neurology department of Aerospace Center Hospital was selected to diagnose the intracranial pressure. According to the needs of the patient's condition, 150 patients underwent lumbar puncture and signed an informed consent form. The patients were divided into 3 groups (n = 47): the age of 18: 40 years old was 18: 40 years old. The intracranial pressure (ICP) of the subjects was measured by FVEP-NIICPM technique, and 47 cases were divided into 4 groups (n = 47): the age group (n = 47) was divided into 4 groups (n = 47). Results there was significant difference between the measured values of FVEP-NIICPM and intracranial pressure of lumbar puncture and the correlation analysis showed that there was a significant difference between the measured value of FVEP-NIICPM and the measured value of intracranial pressure through lumbar puncture. There was a positive correlation between the measured value of FVEP-NIICPM and the value of intracranial pressure measured by lumbar puncture. There was no significant difference in intracranial pressure difference between FVEP-NIICPM technique and lumbar puncture technique. Conclusion the intracranial pressure measured by FVEP-NIICPM technique and lumbar puncture technique is different. There was a statistical difference (P 0.05), but there was a significant positive correlation between the two values, and the absolute difference between the two methods was only 5.5 mm H _ 2O, which basically reflected the actual situation of intracranial pressure and had no effect on the clinical significance. Age had no significant effect on the measurement of intracranial pressure by FVEP-NIICPM.
【作者单位】：辽宁医学院航天中心医院研究生培养基地神经内科;航天中心医院神经内科;
【基金】：北京市自然科学基金(No.152027)
【分类号】：R741.04

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