颅内外动脉粥样硬化狭窄危险因素分析

发布时间：2018-02-14 06:06

本文关键词： 颅内动脉粥样硬化颅外动脉粥样硬化危险因素高尿酸血症　出处：《重庆医科大学》2014年硕士论文　论文类型：学位论文

【摘要】：目的颅内及颅外血管动脉粥样硬化狭窄的危险因素不同，本研究旨在区分不同危险因素与血管动脉粥样硬化狭窄部位的关系。方法我们对260位缺血性脑血管病患者（年龄64±11，男性占56.2%）的脑血管CT血管成像（CT angiography，CTA）结果进行分析并根据狭窄部位及程度进行分组。使用多分类logistic回归模型来分析颅内外血管狭窄的独立危险因素。结果多分类logistic回归分析提示：高血压是颅内血管狭窄的独立危险因素。年龄、高血压、糖尿病是颅外血管狭窄的独立危险因素。年龄、高血压、糖尿病及饮酒是颅外血管中重度狭窄的独立危险因素。年龄、高血压、糖尿病、高胆固醇血症是混合血管狭窄的独立危险因素。年龄和糖尿病是混合血管中重度狭窄的独立危险因素。另外我们还发现高尿酸是颅外血管狭窄的独立危险因素。结论颅内外血管动脉粥样硬化狭窄的危险因素不尽相同，，高血压主要与颅内动脉粥样硬化狭窄相关。而高尿酸是新发现的颅外血管狭窄的独立危险因素。
[Abstract]:Objective to study the risk factors of intracranial and extracranial atherosclerotic stenosis. The aim of this study was to distinguish the relationship between different risk factors and the location of atherosclerotic stenosis. Methods the results of CT angiography (CTAs) in 260 patients with ischemic cerebrovascular disease (age 64 卤11, male 56.2) were compared. Multiple classification logistic regression model was used to analyze the independent risk factors of intracranial and extracranial vascular stenosis. Results multiple logistic regression analysis showed that hypertension was an independent risk factor for intracranial vascular stenosis. Age, hypertension and diabetes were independent risk factors for extracranial vascular stenosis. Diabetes and alcohol consumption are independent risk factors for severe extracranial vascular stenosis. Hypercholesterolemia was an independent risk factor for mixed vascular stenosis, age and diabetes were independent risk factors for moderate and severe stenosis of mixed vessels. We also found that hyperuricemia was an independent risk factor for extracranial vascular stenosis. Conclusion the risk factors of intracranial and extracranial atherosclerotic stenosis are different, hypertension is mainly associated with intracranial atherosclerotic stenosis, and high uric acid is an independent risk factor for newly discovered extracranial vascular stenosis.
【学位授予单位】：重庆医科大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R743.3

【共引文献】