老年脑梗死患者颈动脉硬化与危险因素的相关性

发布时间：2018-02-21 12:30

本文关键词： 脑梗死颈动脉硬化　出处：《中国老年学杂志》2017年03期 　论文类型：期刊论文

【摘要】：目的研究老年脑梗死患者颈动脉硬化与危险因素的相关性。方法用抽样方式选取2015年1~12月该院神经内科收入院的年龄60岁及以上的脑梗死患者450例,平均年龄(70.86±6.82)岁。入院当天进行病史采集,记录有无高血压史、糖尿病史及吸烟史,并于次日清晨对其血液中总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)及空腹血糖(FPG)的浓度进行检测。所有患者均行颈动脉彩超检查,按照检查结果分为正常组、斑块组及狭窄组。结果三组年龄、高血压、糖尿病、吸烟、LDL-C及FPG水平差异显著(P0.05)。行多因素Logistic分析,校正其他因素后,年龄、吸烟、LDL-C为颈动脉硬化的独立危险因素(P0.05);与其他三组比较,合并高血压和糖尿病组的颈动脉硬化患病率及颈动脉内中膜厚度(IMT)积分均较高(P0.01)。结论年龄、吸烟、LDL-C、高血压及糖尿病与脑梗死患者颈动脉硬化的形成及发展有明显相关性,对于合并上述危险因素的患者,应早期进行颈动脉彩超检查,以控制脑血管事件的发生。
[Abstract]:Objective to study the correlation between carotid atherosclerosis and risk factors in elderly patients with cerebral infarction. The average age was 70.86 卤6.82 years. The history of hypertension, diabetes and smoking were recorded on the day of admission. The concentrations of TC, TG, LDL-C and FPG in their blood were detected in the morning of next day. All the patients were divided into normal group according to the results of carotid ultrasonography. Results there were significant differences in age, hypertension, diabetes, smoking, LDL-C and FPG levels among the three groups (P 0.05). Multivariate Logistic analysis was performed, and other factors were adjusted for age. Compared with the other three groups, the prevalence rate of carotid atherosclerosis and IMT score in hypertension and diabetes group were higher than those in other three groups. LDL-C, hypertension and diabetes were significantly correlated with the formation and development of carotid atherosclerosis in patients with cerebral infarction. In order to control the occurrence of cerebrovascular events, carotid color ultrasound should be performed early in patients with these risk factors.
【作者单位】：吉林大学白求恩第一医院;亳州市人民医院;青岛市立医院;
【分类号】：R543.4

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