芪红利水饮配合微创血肿清除术治疗脑出血的临床研究

发布时间：2018-02-21 14:37

本文关键词： 脑出血微创血肿清除术芪红利水饮益气活血化瘀利水临床研究　出处：《河南中医学院》2014年硕士论文　论文类型：学位论文

【摘要】：目的：比较芪红利水饮配合微创血肿肿清除术与微创血肿清除术治疗脑出血的效果及安全性，阐明芪红利水饮配合微创血肿清除术的确切疗效。方法：以2011年11月至2014年1月间我科收治的原发性幕上脑出血患者(30mml~60ml)50例为研究对象，对微创血肿清除术后患者按照患者或直系亲属意愿进行分组，将患者分为芪红利水饮配合微创血肿清除术组（简称加中药组）29例和微创血肿清除术治疗组(简称微创组)21例，，比较两组患者微创血肿清除术术后7天后格拉斯哥意识障碍评分(Glasgow coma scale，GCS)，血肿体积变化百分比，中医证候评分，对3个月后的生存质量行格拉斯哥预后评分(Glasgowoutcome scale，GOS)并予以分析。结果：本项研究中，加中药组较微创组术后7天后中药组的血肿体积显著缩小，血肿体积变化百分比明显高于微创组（P0.001），平均GCS评分明显高于微创组（P0.001），中医症候评分明显高于微创组（P0.001），但患者长期预后方面与单用微创血肿清除术无明显差异，即二者均可改善患者长期预后。结论：与微创组比较，加中药组能显著改善脑出血患者的意识障碍，缩减血肿体积、减轻占位效应，改善中医症候评分，但患者长期预后方面与单用微创血肿抽吸引流术无明显差异，即二者均可改善患者长期预后。
[Abstract]:Objective: to compare the efficacy and safety of Qijianshui decoction combined with minimally invasive hematoma removal and minimally invasive hematoma removal in the treatment of intracerebral hemorrhage, and to elucidate the exact effect of Qijianshui decoction combined with minimally invasive hematoma removal. Methods: 50 patients with primary supratentorial intracerebral hemorrhage treated from November 2011 to January 2014 were divided into groups according to the wishes of the patients or their immediate relatives after minimally invasive hematoma removal. The patients were divided into two groups: Qijiuhuiyin combined with minimally invasive hematoma removal (29 cases) and minimally invasive hematoma removal group (21 cases). Glasgow coma scale scale, hematoma volume change percentage, TCM syndrome score, Glasgow outcome score (Glasgow outcome scale) and Glasgow outcome scale (GOS) were compared between the two groups 7 days after minimally invasive hematoma clearance. Results: in this study, the hematoma volume in the treatment group was significantly smaller than that in the minimally invasive group 7 days after operation. The percentage of hematoma volume change was significantly higher than that in the minimally invasive group (P 0.001), the average GCS score was significantly higher than that in the minimally invasive group (P 0.001), the TCM symptom score was significantly higher than that in the minimally invasive group (P 0.001), but there was no significant difference between the long-term prognosis of the patients and that of minimally invasive hematoma clearance alone. That is, both can improve the long-term prognosis of patients. Conclusion: compared with the minimally invasive group, the traditional Chinese medicine group can significantly improve the disturbance of consciousness, reduce the volume of hematoma, reduce the space occupying effect and improve the score of TCM symptoms in patients with intracerebral hemorrhage. However, there was no significant difference in the long term prognosis between the patients and the minimally invasive hematoma aspiration and drainage alone, that is, both of them could improve the long term prognosis of the patients.
【学位授予单位】：河南中医学院
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R743.34

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