血清同型半胱氨酸与心脑血管病变的相关性研究

发布时间：2018-02-23 04:40

  本文关键词： 同型半胱氨酸 心脑血管 脑梗死　出处：《国际检验医学杂志》2016年19期 　论文类型：期刊论文

【摘要】：目的探讨血清同型半胱氨酸(Hcy)水平与心脑血管病变的相关性。方法采用循环酶法检测该院神经内科脑梗死患者102例,内分泌科糖尿病患者96例和100例健康体检者的血清Hcy水平,并进行比较。结果脑梗死患者分为单纯合并高血压组与合并高血压高血糖组,2组患者Hcy水平均显著高于健康对照组的(8.600±2.759)μmol/L,差异有统计学意义(P0.05);但2组之间差异无统计学意义(P0.05)。糖尿病患者分为单纯糖尿病患者组和糖尿病合并心脑血管患者组,后者Hcy水平[(17.220±4.165)μmol/L]显著高于前者[(8.940±2.845)μmol/L],差异有统计学意义(P0.05)。结论 Hcy是心脑血管疾病发生的独立危险因素,及早筛查高危人群并采取有效的预防措施,可降低其发病率。
[Abstract]:Objective to investigate the relationship between serum homocysteine cysteine (HCH) level and cardiovascular and cerebrovascular diseases. Methods Serum Hcy levels in 102 patients with cerebral infarction in neurology department, 96 patients with diabetes mellitus in endocrine department and 100 healthy controls were detected by circulating enzyme method. Results the levels of Hcy in patients with cerebral infarction were significantly higher than those in healthy controls (8.600 卤2.759) 渭 mol / L, but there was no significant difference between the two groups, but there was no significant difference between the two groups. Diabetic patients were divided into simple diabetes group and diabetes complicated with cardio-cerebrovascular disease group. The Hcy level of the latter [17.220 卤4.165 渭 mol/L] was significantly higher than that of the former [8.940 卤2.845 渭 mol/L], and the difference was statistically significant (P 0.05). Conclusion Hcy is an independent risk factor for the occurrence of cardiovascular and cerebrovascular diseases.
【作者单位】： 河南省直第三人民医院检验科;河南省直第三人民医院神经内科;河南省直第三人民医院内分泌科;
【分类号】：R54;R743;R446.1
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本文编号：1526143