血管内完全栓塞颅内动脉瘤的影响因素分析

发布时间：2018-02-24 09:02

本文关键词： 颅内动脉瘤介入栓塞完全栓塞相关因素　出处：《中国脑血管病杂志》2017年10期 　论文类型：期刊论文

【摘要】：目的分析颅内动脉瘤血管内完全栓塞的影响因素。方法回顾性分析安徽医科大学附属安徽省立医院神经外科2013年1月至2017年1月行介入栓塞治疗的546例单发颅内动脉瘤住院患者的临床资料及影像学资料,将所有患者按照动脉瘤即刻栓塞程度,分为完全栓塞组(255例)和非完全栓塞组(291例),采用单因素、多因素Logistic回归分析方法,分析与颅内动脉瘤完全栓塞的相关因素。结果单因素分析显示,完全栓塞组与非完全栓塞组患者动脉瘤是否破裂、解剖形态、Hunt-Hess分级、动脉瘤大小及瘤颈宽度、不同治疗方案、动脉瘤角度差异均有统计学意义(均P0.05)。多因素回归分析结果显示,动脉瘤大小(OR=0.344,95%CI:0.204~0.578,P0.01)、是否破裂(OR=0.568,95%CI:0.314~0.947,P=0.030)、栓塞方式(OR=3.699,95%CI:2.223~6.153,P0.01)、瘤颈宽度(OR=0.326,95%CI:0.198~0.539,P=0.003)、动脉瘤角度(OR=0.647,95%CI:0.451~0.928,P=0.018)、动脉瘤形态(OR=1.689,95%CI:1.118~2.552,P=0.013)是影响颅内动脉瘤完全栓塞的独立因素。结论微小动脉瘤、未破裂动脉瘤、窄颈动脉瘤、小夹角动脉瘤、规则动脉瘤、支架或球囊辅助更易于完全栓塞颅内动脉瘤。
[Abstract]:Objective to analyze the influencing factors of complete endovascular embolization of intracranial aneurysms. Methods the interventional embolization of 546 cases of intracranial aneurysms treated by interventional embolization from January 2013 to January 2017 in Anhui Provincial Hospital affiliated to Anhui Medical University was retrospectively analyzed. Clinical and imaging data of inpatients with aneurysm, According to the degree of immediate embolization of aneurysms, all patients were divided into complete embolization group (255 cases) and incomplete embolization group (291 cases). Univariate and multivariate Logistic regression analysis was used. Results univariate analysis showed whether the aneurysm was ruptured, the anatomic morphology was Hunt-Hess grade, the size of aneurysm, the width of the aneurysm neck, and the different treatment plan, between the complete embolization group and the incomplete embolization group. There were significant differences in the angle of aneurysm (all P 0.05). The results of multivariate regression analysis showed that, The size of the aneurysm OR0.344-95CII: 0.2040.578P0.01, the angle of the aneurysm OR0.6495CI0.3140.947P0.030, the mode of embolization OR3.69995 CI 2.2236.153P0.01. the width of the neck OR0.32695CI0.198 0.539P0.003, the angle of the aneurysm 0.64795CI0.4510.928P0.018, the shape of the aneurysm OR1.68995CI1.1182.552Pl 1.1182.552P0. 01313) are the independent factors affecting the complete embolization of the aneurysm. Conclusion: the aneurysm is not ruptured, the carotid aneurysm is narrow and the aneurysm is narrow. Small angle aneurysms, regular aneurysms, stents or balloon aids are more likely to completely embolize intracranial aneurysms.
【作者单位】：安徽医科大学附属省立医院神经外科;
【基金】：安徽省自然科学基金项目(1608085MH210)
【分类号】：R743

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