脑卒中后抑郁与神经功能缺损关系研究

发布时间：2018-02-27 14:55

本文关键词： 卒中抑郁日常生活活动神经心理学测验　出处：《中国现代神经疾病杂志》2016年05期 　论文类型：期刊论文

【摘要】：目的探讨脑卒中后抑郁与神经功能缺损程度和日常生活活动能力的相关性。方法采用抑郁自评量表、汉密尔顿抑郁量表17项、美国国立卫生研究院卒中量表、Barthel指数对160例脑卒中患者进行抑郁、神经功能缺损和日常生活活动能力评价。结果 160例脑卒中患者中65例(40.63%)出现抑郁症状。与无抑郁组相比,抑郁组患者神经功能缺损程度更重(P=0.045)、日常生活活动能力更低(P=0.000)。进一步将脑卒中后抑郁患者分为轻度、中度和重度抑郁亚组,随着抑郁程度的增加,神经功能缺损加重(P=0.000,0.000,0.000)、日常生活活动能力下降(P=0.000,0.000,0.000)。Pearson相关分析显示,抑郁症状与神经功能缺损程度呈正相关(r=0.534,P=0.005),与日常生活活动能力呈负相关(r=-0.645,P=0.002)。结论脑卒中后抑郁与神经功能缺损程度和日常生活活动能力相关,积极治疗原发病、减轻神经功能缺损、早期康复治疗、提高日常生活活动能力,将有助于减轻脑卒中后抑郁程度。
[Abstract]:Objective to investigate the relationship between depression after stroke and the degree of neurological impairment and activities of daily living. Methods Self-rating Depression scale (SDS) and Hamilton Depression scale (Hamilton Depression scale) were used. The National Institutes of Health Stroke scale and Barthel Index were used to evaluate the depression, neurological impairment and activities of daily living (ADL) in 160 stroke patients. The degree of neurological deficit in depression group was more severe than that in control group, and the activity of daily living was lower. The patients with depression after stroke were further divided into mild, moderate and severe depression subgroups, and with the increase of depression degree, the patients with depression were divided into mild, moderate and severe depression subgroups. The neurologic deficit was aggravated by 0.000 ~ 0.000 ~ 0.000 ~ 0.000, and the activity of daily living decreased by 0.000 ~ 0.000 ~ 0.000 ~ 0.000 ~ 0.000 ~ 0.000 ~ 0.000 ~ 0.000. Pearson correlation analysis showed that. There was a positive correlation between depressive symptoms and the degree of neurological deficit, and a negative correlation between depression and ADL activity. Conclusion Depression after stroke is related to the degree of neurological deficit and activity of daily life, and can be used to treat the primary disease. Reducing neurological deficit, early rehabilitation and improving activities of daily life will help to alleviate depression after stroke.
【作者单位】：首都医科大学附属北京世纪坛医院神经内科;
【分类号】：R743.3;R749.4

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