早期差别化降血压治疗急性脑出血的疗效研究

发布时间：2018-03-04 23:20

本文选题：脑出血　切入点：降压　出处：《临床合理用药杂志》2016年33期 　论文类型：期刊论文

【摘要】：目的探讨早期差别化降血压治疗急性脑出血的临床疗效。方法选取2013年1月—2015年8月桂林医学院第二附属医院收治的急性脑出血患者102例,随机分成对照组与治疗组,各51例。对照组患者给予常规降血压治疗,治疗组患者给予差别化降血压治疗。比较两组患者治疗前后血肿体积、美国国立卫生院卒中量表(NIHSS)评分、临床疗效。结果治疗前两组患者的血肿体积比较,差异无统计学意义(P0.05);治疗后治疗组小出血量患者血肿体积小于对照组,差异有统计学意义(P0.05);治疗后两组大出血量患者血肿体积比较,差异无统计学意义(P0.05)。治疗前两组患者NIHSS评分比较,差异无统计学意义(P0.05);治疗后治疗组小出血量患者NIHSS评分低于对照组,差异有统计学意义(P0.05);治疗后两组大出血量患者NIHSS评分比较,差异无统计学意义(P0.05)。观察组小出血量患者总有效率高于对照组,差异有统计学意义(P0.05);两组大出血量患者总有效率比较,差异无统计学意义(P0.05)。结论急性脑出血患者应用早期差别化降血压治疗能明显改善小出血量患者的临床疗效,可有效改善患者神经功能缺损情况,但是对于大出血量患者疗效不明显。
[Abstract]:Objective to investigate the clinical efficacy of early differential hypotension in the treatment of acute cerebral hemorrhage. Methods 102 patients with acute cerebral hemorrhage treated in the second affiliated Hospital of Guilin Medical College from January 2013 to August 2015 were randomly divided into control group and treatment group. Patients in the control group were treated with conventional hypotension therapy, and the patients in the treatment group were treated with differential hypotension therapy. The volume of hematoma was compared between the two groups before and after treatment, and the NIHSS score was evaluated by the National Institutes of Health Stroke scale. Results there was no significant difference in hematoma volume between the two groups before treatment, and the hematoma volume in the treatment group was smaller than that in the control group after treatment. There was no significant difference in hematoma volume between the two groups after treatment, and there was no significant difference in hematoma volume between the two groups after treatment. The NIHSS scores of the two groups were compared before and after treatment, and there was no significant difference in the volume of hematoma between the two groups before treatment. After treatment, the NIHSS score of the patients with small bleeding volume in the treatment group was lower than that in the control group, and the difference was statistically significant (P 0.05). The total effective rate of the observation group was higher than that of the control group, and the difference was statistically significant (P 0.05), the total effective rate of the two groups was higher than that of the control group, and the total effective rate of the two groups was higher than that of the control group. Conclusion early differential hypotension therapy in patients with acute intracerebral hemorrhage can obviously improve the clinical effect of patients with small amount of blood loss, and can effectively improve the neurological deficit in patients with acute intracerebral hemorrhage. But the curative effect is not obvious for the patient with large amount of blood loss.
【作者单位】：桂林医学院第二附属医院急诊科;
【分类号】：R743.34

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